
Cortisol, often known as the 'stress hormone', is produced by the adrenal glands and helps to regulate your metabolism and reduce inflammation. It also raises your blood sugar levels and blood pressure in preparation for physical activity. As part of your circadian rhythm, there is usually a spike in cortisol in the early hours of the morning that helps you to wake up feeling refreshed.
| Characteristics | Values |
|---|---|
| Name | Cortisol |
| Other Names | Stress hormone |
| Produced By | Adrenal glands |
| Functions | Regulate metabolism, reduce inflammation, raise blood sugar levels, raise blood pressure |
| Release | Usually spikes in the early morning to help you wake up |
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What You'll Learn
- Cortisol, the stress hormone, is released in the morning to help you wake up
- Cortisol levels are higher in the morning and lower at night
- Melatonin, the sleep hormone, is released at night to help you sleep
- The SCN (suprachiasmatic nucleus) in the brain controls your body's internal clock
- The optic nerve in your eyes senses morning light, triggering the release of cortisol

Cortisol, the stress hormone, is released in the morning to help you wake up
Cortisol, often referred to as the 'stress hormone', is released in the morning to help you wake up. It is produced by your adrenal glands and helps to regulate your metabolism and reduce inflammation. When cortisol is released, it raises your blood sugar levels and blood pressure in preparation for physical activity. As part of your circadian rhythm, there is usually a spike in cortisol in the early hours of the morning that helps you to wake up feeling refreshed. As the day progresses, your levels of cortisol will gradually decline as more melatonin (the sleep hormone) is released in the hours before you go to bed.
Cortisol is triggered by the SCN (suprachiasmatic nucleus), an area of the brain that controls your body's internal clock. The SCN is located in the hypothalamus and is sensitive to signals of dark and light. When your optic nerve senses the morning light, it triggers the release of cortisol and other hormones to help you wake up.
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Cortisol levels are higher in the morning and lower at night
Cortisol, often known as the 'stress hormone', is produced by the adrenal glands. It helps to regulate your metabolism and reduce inflammation. Cortisol levels are higher in the morning and lower at night. When cortisol is released, it raises your blood sugar levels and blood pressure in preparation for physical activity. As part of your circadian rhythm, there is usually a spike in cortisol in the early hours of the morning that helps you to wake up feeling refreshed. As the day progresses, your levels of cortisol will gradually decline as more melatonin is released in the hours before you go to bed.
Cortisol is triggered by the SCN (suprachiasmatic nucleus), an area of the brain that is sensitive to signals of dark and light. The optic nerve in your eyes senses the morning light, which then triggers the release of cortisol and other hormones to help you wake up.
If you are under acute stress, or you have been under chronic stress, you may notice that you tend to wake up between 2-4 am and have difficulty falling back asleep.
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Melatonin, the sleep hormone, is released at night to help you sleep
Cortisol is often referred to as the 'stress hormone' and is produced by the adrenal glands. It helps to regulate your metabolism and reduce inflammation. When cortisol is released, it raises your blood sugar levels and blood pressure in preparation for physical activity. As part of your circadian rhythm, there is usually a spike in cortisol in the early hours of the morning that helps you to wake up feeling refreshed.
Melatonin, or the 'sleep hormone', is made by the pineal gland and works with cortisol. Normally, at night time, melatonin levels will naturally increase, and cortisol levels will naturally be lower. As the day progresses, your levels of cortisol will gradually decline as more melatonin is released in the hours before you go to bed.
Your body's internal clock is controlled by an area of the brain called the SCN (suprachiasmatic nucleus). The SCN is located in the hypothalamus and is sensitive to signals of dark and light. The optic nerve in your eyes senses the morning light, then the SCN triggers the release of cortisol and other hormones to help you wake up.
If you are under acute stress, or you have been under chronic stress, you may notice that you tend to wake up between 2-4 am and have difficulty falling back asleep.
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The SCN (suprachiasmatic nucleus) in the brain controls your body's internal clock
The suprachiasmatic nucleus (SCN) is a small region of the brain in the hypothalamus, situated directly above the optic chiasm. It is responsible for regulating sleep cycles in animals by controlling the body's internal clock.
The SCN plays a central role in the daily programming of organismic functions by regulating day-to-day oscillations of the internal milieu and synchronizing them to the changing cycles of day and night and of body state. This biological clock drives the daily expression of vital homeostatic functions as diverse as feeding, drinking, body temperature, and neurohormone secretion. It adaptively organizes these body functions into near-24-hour oscillations termed circadian rhythms.
The SCN achieves this temporal order through two mechanisms:
- Generating output signals that relay time-of-day information
- Gating its own sensitivity to incoming signals that adjust clock timing
The SCN is highly influenced by the input of light, which is detected in the eye by receptors called intrinsically photosensitive retinal ganglion cells (ipRGC) that contain the photopigment melanopsin. These cells send signals to the SCN via the retinohypothalamic tract, a connection that extends from the retina of the eye to the anterior hypothalamus.
Disruptions or damage to the SCN has been associated with different mood disorders and sleep disorders, highlighting the significance of the SCN in regulating circadian timing.
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The optic nerve in your eyes senses morning light, triggering the release of cortisol
The SCN (suprachiasmatic nucleus) in the brain is sensitive to signals of dark and light. When the optic nerve in your eyes senses the morning light, the SCN triggers the release of cortisol and other hormones to help you wake up. Normally, at night time, melatonin levels will naturally increase, and cortisol will naturally be lower. If you are under acute stress, or you have been under chronic stress, you may notice that you tend to wake up between 2-4 am and have difficulty falling back asleep.
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Frequently asked questions
Cortisol, also known as the 'stress hormone', is released in the early morning to help you wake up.
Cortisol raises your blood sugar levels and blood pressure in preparation for physical activity.
Cortisol levels gradually decline as the day progresses and more melatonin is released in the hours before you go to bed.
Melatonin is the 'sleep hormone' that works with cortisol to regulate your sleep/wake cycle.
If you're under acute or chronic stress, you may find yourself waking up between 2-4 am and struggling to fall back asleep.











































