
Unisom SleepGels are soft liquid gel capsules that help troubled sleepers fall asleep quickly and wake up feeling refreshed. The active ingredient in Unisom SleepGels is diphenhydramine, an antihistamine that blocks the effects of histamine, a naturally occurring neurotransmitter that can keep you awake. Unisom SleepGels are non-habit-forming and safe when used as directed for occasional sleeplessness. However, they may cause side effects such as dry mouth, constipation, and confusion, especially in older adults. It is important to follow the directions on the label and consult a doctor or healthcare professional if you have any questions or concerns about using Unisom SleepGels.
| Characteristics | Values |
|---|---|
| Brand Name | Unisom SleepGels |
| Generic Name | Diphenhydramine |
| Other Brand Names | Banophen, Benadryl, Dibenil, Diphen, Hydramine, Nervine, Nytol, QlearQuil, Simply Sleep, Sominex, ZzzQuil |
| Other Generic Names | Diphenhydramine citrate, diphenhydramine HCl, diphenhydramine hydrochloride, diphenhydramine tannate |
| Forms | Capsule, liquid, tablet, chewable tablet |
| Function | Blocks the effects of histamine, a naturally-occurring neurotransmitter that can keep you awake |
| Side Effects | Dizziness, drowsiness, stomach upset, dry mouth, constipation, confusion, blurred vision, photosensitivity, excitability in children |
| Precautions | Do not use to make a child sleepy, do not drive or operate machinery after taking, consult a doctor if sleeplessness persists for more than two weeks |
| Other Uses | Treating allergy or common cold symptoms, allergic reactions, motion sickness, or certain movement problems |
| Variants | SleepGels, SleepMinis, SleepMelts, PM Pain, Simple Slumbers |
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What You'll Learn

Unisom Sleep Gels' active ingredient
Unisom Sleep Gels are soft liquid gel capsules that help troubled sleepers fall asleep fast and wake up feeling refreshed. The active ingredient in Unisom Sleep Gels is diphenhydramine, which is an antihistamine. Antihistamines work by blocking the effects of histamine, a naturally occurring neurotransmitter that can keep you alert and awake. By blocking histamine, diphenhydramine can create a sedating effect, helping you fall asleep faster.
Diphenhydramine is also known by the generic names diphenhydramine citrate, diphenhydramine HCl, diphenhydramine hydrochloride, and diphenhydramine tannate. It is a common ingredient in many over-the-counter (OTC) sleep aids and allergy medications. When used for sleep, it is important to follow the directions on the label or as prescribed by a doctor. Unisom Sleep Gels are intended for short-term use for occasional sleeplessness. If sleeplessness persists for more than two weeks, it is recommended to consult a doctor as it may be a symptom of a serious underlying medical condition.
Diphenhydramine can cause side effects such as drowsiness, dizziness, stomach upset, and blurred vision. It can also increase sensitivity to sunlight, causing severe sunburns, blisters, and swelling. People who are 60 and older or younger than 18 may be at greater risk of experiencing side effects. It is important to speak to a healthcare provider before taking diphenhydramine to understand the potential risks and interactions with other medications or supplements.
It is important to note that Unisom Sleep Gels are not intended to be used in children to induce sleep. Antihistamines, when misused in very young children, can lead to serious consequences, including death. Always follow the directions on the medicine label regarding giving Unisom Sleep Gels to a child and consult a doctor or pharmacist if you have any questions or concerns about the product's safety or suitability for your specific circumstances.
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How to take Unisom Sleep Gels
Unisom Sleep Gels are soft liquid gel capsules that contain diphenhydramine, a histamine blocker that helps you fall asleep faster and get a full night's sleep. Unisom Sleep Gels are non-habit-forming and safe when used as directed for occasional sleeplessness. It is important to note that Unisom Sleep Gels are for adults only and should not be used to make a child sleepy as it can lead to serious side effects.
- Unisom Sleep Gels should be taken as directed on the label or as prescribed by your doctor. The recommended dose for adults is one tablet, taken within 30 minutes before bedtime.
- The tablet should be chewed before swallowing. For liquid medicine, use the provided dosing syringe or a medicine dose-measuring device to ensure an accurate dose.
- Unisom Sleep Gels can be taken with or without food. However, if you are using it for motion sickness, it is recommended to continue taking it with meals and at bedtime during the period of your travel.
- Unisom Sleep Gels should only be used for short-term relief of occasional sleeplessness. If your sleeplessness persists for more than two weeks, consult your doctor as it may be a symptom of a more serious underlying medical condition.
- Do not use Unisom Sleep Gels if you are allergic to any of its ingredients. Always check the label for a complete list of ingredients and warnings.
- Unisom Sleep Gels may interact with other medicines and supplements. Inform your healthcare provider about any other medications or supplements you are currently taking to ensure safe use.
- Unisom Sleep Gels may cause side effects such as drowsiness, dizziness, dry mouth, constipation, and confusion, especially in older adults. Do not drive or operate heavy machinery until you know how Unisom Sleep Gels affect you.
- If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
- Store Unisom Sleep Gels in a cool, dry place, away from direct sunlight or moisture. Keep it out of the reach of children and pets.
- If you have any questions or concerns about taking Unisom Sleep Gels, always consult your doctor or healthcare provider for personalized advice.
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Side effects of Unisom Sleep Gels
Unisom Sleep Gels are used to treat insomnia or trouble sleeping. The active ingredient in Unisom Sleep Gels is diphenhydramine, an antihistamine that blocks the effects of histamine in the body, causing drowsiness and helping you fall asleep faster. Unisom Sleep Gels are intended for adults and children aged 12 and above. They are to be taken once daily, 30 minutes before bedtime, and only for relief from occasional sleeplessness. If sleeplessness persists for more than two weeks, consult your doctor as it may be a symptom of a serious underlying medical condition.
While Unisom Sleep Gels can be effective in aiding sleep, they may also cause several side effects, especially for those aged 60 and above or younger than 18. The most common side effects include drowsiness, dizziness, and stomach upset. It may also cause excitability in children. People taking Unisom Sleep Gels are advised not to drive or engage in activities that require alertness, coordination, or clear vision until they know how the drug affects them.
Other side effects of Unisom Sleep Gels include dry mouth, constipation, and confusion, which may be more likely in older adults. Diphenhydramine can also increase photosensitivity, making your skin more sensitive to sunlight, sunlamps, and tanning beds. This increased sensitivity can lead to severe sunburns, blisters, and swelling. To mitigate this risk, individuals who need to be in the sun should wear sunscreen, protective clothing, and a hat.
In rare cases, an overdose of Unisom Sleep Gels can lead to fatal consequences. Symptoms of an overdose include vomiting, confusion, severe drowsiness, ringing in the ears, dry eyes and mouth, dilated pupils, fast heart rate, tremors, agitation, hallucinations, or seizures. If you or someone else experiences these symptoms, seek immediate medical help or call the Poison Control Center at 1-800-222-1222.
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Precautions when taking Unisom Sleep Gels
Unisom Sleep Gels are an antihistamine medication that contains diphenhydramine HCl as the active ingredient. They are used to treat insomnia and occasional sleeplessness in adults and children over 12 years of age. It is important to take certain precautions when using this medication to ensure safe and effective use. Here are some key precautions to keep in mind:
- Age restrictions: Unisom Sleep Gels are not recommended for children under 12 years old. Always follow the directions on the medicine label and consult a healthcare provider if you have any questions.
- Pregnancy and breastfeeding: If you are pregnant or breastfeeding, it is important to consult a health professional before taking Unisom Sleep Gels.
- Allergy warnings: Although rare, some people may experience an allergic reaction to Unisom Sleep Gels. Stop taking the medication and seek emergency medical help if you experience symptoms such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
- Side effects: Unisom Sleep Gels may cause side effects such as dry mouth, constipation, confusion (especially in older adults), dizziness, drowsiness, and stomach upset. If you experience any unusual symptoms, consult your healthcare provider.
- Drug interactions: Diphenhydramine may interact with other medications, including prescription pain medicines, sleep medicines, and medicines for anxiety. Always inform your healthcare provider about any other medications or supplements you are taking to ensure safe use.
- Photosensitivity: Diphenhydramine can increase photosensitivity, making your skin more sensitive to sunlight, sunlamps, and tanning beds. If you need to be exposed to sunlight, take appropriate precautions such as wearing sunscreen, a hat, and protective clothing.
- Alertness and coordination: Unisom Sleep Gels may cause drowsiness, dizziness, and blurred vision. Do not drive or engage in activities that require alertness or coordination until you know how this medication affects you.
- Duration of use: Unisom Sleep Gels are intended for occasional sleeplessness. If sleeplessness persists for more than two weeks, consult your healthcare provider as it could indicate an underlying medical condition.
- Accurate dosing: When taking the liquid form of Unisom Sleep Gels, use an accurate measuring device, such as the provided syringe or a medicine dose-measuring device. Do not use household spoons as they may lead to incorrect dosing.
- Storage and expiration: Store Unisom Sleep Gels in a cool, dry place, out of the reach of children. Do not use the product after the expiration date printed on the package.
- Medical conditions: Consult your healthcare provider before taking Unisom Sleep Gels if you have any medical conditions, especially breathing problems such as asthma or COPD.
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Unisom Sleep Gels' suitability for children
Unisom Sleep Gels are not suitable for children under 12 years old. The product is intended for adults and children over 12 years old who are experiencing occasional sleeplessness. The active ingredient in Unisom Sleep Gels is diphenhydramine, which is an antihistamine that blocks the effects of histamine in the body, making users sleepy. While the product is non-habit-forming and safe when used as directed, it is important to follow the directions on the label and not exceed the recommended dosage.
Diphenhydramine can cause side effects such as daytime drowsiness, dry mouth, dizziness, and memory problems. It can also affect alertness and coordination, and may cause blurry vision. These side effects may be more likely or pronounced in older adults. In addition, diphenhydramine can increase photosensitivity, making the skin more sensitive to sunlight, sunlamps, and tanning beds. This can lead to severe sunburns, blisters, and swelling. As such, it is recommended to wear sunscreen, a hat, and protective clothing when exposed to sunlight after taking Unisom Sleep Gels.
It is important to note that Unisom Sleep Gels should not be used to make a child sleepy. While it can be effective for adults and older children experiencing occasional sleeplessness, it is not intended as a sleep aid for younger children. In fact, misuse of antihistamines in very young children can lead to serious health risks, including death. Therefore, it is crucial to keep Unisom Sleep Gels out of the reach of children and to consult a healthcare provider if you have any questions or concerns about its use.
If you are experiencing sleeplessness for more than two weeks, it is recommended to consult a doctor as it may be a symptom of a serious underlying medical condition. Additionally, if you are pregnant or breastfeeding, or taking other medications, it is important to speak to a healthcare professional before using Unisom Sleep Gels to ensure it is safe and appropriate for your individual circumstances.
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Frequently asked questions
Unisom Sleep Gels are soft liquid gel capsules that help troubled sleepers fall asleep fast and wake up feeling refreshed.
The active ingredient in Unisom Sleep Gels is diphenhydramine, an antihistamine that blocks the effects of histamine in the body, which helps you fall asleep faster.
Unisom Sleep Gels may cause side effects such as dry mouth, constipation, and confusion, especially in older adults. Other common side effects include drowsiness, dizziness, and upset stomach. It may also cause excitability in children.


























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