
Sleep deprivation can have serious effects on the human body, including hallucinations, delusions, and conditions resembling acute psychosis. While the effects of sleep deprivation on individuals have been widely studied, the use of stimulants to stay awake for extended periods has also been examined. The longest reported period of stimulant-induced wakefulness was approximately seven days, achieved by patients using the central nervous system stimulant Captagon, which contains the psychoactive substance fenethylline. However, it is important to note that disrupted sleep patterns and insomnia are common side effects of chronic stimulant use, and the relationship between amphetamine use and acute psychosis has received significant attention.
| Characteristics | Values |
|---|---|
| Name of the person | Randy Gardner |
| Year | 1963/1964 |
| Age | 17 years |
| Number of days without sleep | 11 days |
| Number of hours without sleep | 264 hours |
| Minutes without sleep | 24 minutes |
| Drugs consumed | Coca-Cola |
| Side effects | Mood changes, problems with concentration, short-term memory, paranoia, hallucinations |
| Post-experiment sleep duration | 14 hours and 46 minutes |
| Post-experiment sleep schedule | Awoke naturally around 8:40 p.m., stayed awake until 7:30 p.m. the next day, then slept for 10.5 hours |
| Long-term effects | Serious insomnia decades later |
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What You'll Learn
- The current record for staying awake without drugs is 264 hours and 25 minutes
- Randy Gardner, the record holder, experienced many side effects, including nausea
- Amphetamine-induced psychosis can cause hallucinations and delusions
- Captagon, a stimulant, can cause insomnia and sleep deprivation
- Sleep deprivation can cause paranoia, memory issues, and mood changes

The current record for staying awake without drugs is 264 hours and 25 minutes
To break the previous record of 260 hours held by Tom Rounds, Gardner stayed awake for 264 hours, breaking the world record. Gardner's attempt was carefully monitored and documented. Sleep researcher Dr. William C. Dement and Lt. Cmdr. John J. Ross, who monitored his health, reported varying effects of sleep deprivation on Gardner. While Dement claimed that Gardner showed little effect other than mood changes associated with tiredness, Ross reported serious cognitive and behavioral changes, including moodiness, concentration issues, short-term memory problems, paranoia, and hallucinations.
Gardner's record was broken multiple times until 1997 when Guinness World Records stopped accepting new attempts due to safety concerns. Since then, Guinness World Records has removed all information about sleep deprivation from its books. Despite the health risks associated with severe sleep loss, some individuals have continued to attempt breaking the record.
The effects of sleep deprivation can be significant, even after a single night of missed sleep. Difficulty staying awake, confusion, disorientation, and immune system disruption can occur after 24 to 48 hours without sleep. Prolonged sleep deprivation can lead to hallucinations and other serious health consequences. While dying from sleep deprivation is rare, it is possible, and the long-term effects on overall health are still unclear.
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Randy Gardner, the record holder, experienced many side effects, including nausea
In 1963, Randy Gardner, a 17-year-old boy from San Diego, California, broke the world record for staying awake the longest. Gardner managed to stay awake for 11 days and 24 minutes (approximately 264 hours), breaking the previous record of 260 hours held by Tom Rounds. Gardner's record was monitored and carefully documented by Stanford sleep researcher Dr. William C. Dement, with his health being observed by Lt. Cmdr. John J. Ross.
During his attempt, Gardner experienced several side effects due to sleep deprivation. On the third day, he reported feeling nauseous and discovered that eating citrus fruits like tangerines or oranges helped alleviate the nausea. As the experiment progressed, Gardner began to exhibit signs of cognitive and behavioural changes, including moodiness, problems with concentration and short-term memory, paranoia, and hallucinations. On the eleventh day, he struggled with basic subtraction and forgot what he was doing mid-task. Despite these challenges, Gardner appeared to be in good health at a press conference on the final day of his record-breaking attempt.
After completing the experiment, Gardner slept for 14 hours and 46 minutes, waking up naturally around 8:40 p.m. He stayed awake until approximately 7:30 p.m. the next day, when he slept for an additional ten and a half hours. While he appeared to recover well initially, Gardner reported experiencing serious insomnia around 2007, decades after his sleep experiment, believing that his participation in the 1960s sleep study was a contributing factor.
Due to the potential health risks associated with severe sleep deprivation, Guinness World Records ceased accepting new attempts for the longest period without sleep. The final record recognized by Guinness was held by Robert McDonald, who stayed awake for 453 hours and 40 minutes (18 days, 21 hours, and 40 minutes) in 1986.
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Amphetamine-induced psychosis can cause hallucinations and delusions
Amphetamine-induced psychosis is a mental health condition that belongs to the broader category of substance-induced psychotic disorders. It involves experiencing psychotic symptoms as a result of amphetamine use. Amphetamines are stimulants that can induce psychosis, particularly when chronically abused or used in high doses.
Amphetamine-induced psychosis can lead to hallucinations and delusions, among other symptoms. Hallucinations refer to perceiving things that are not present or experiencing sensory phenomena without an external stimulus. Auditory hallucinations, such as hearing voices or sounds that others cannot hear, are commonly associated with amphetamine-induced psychosis. Visual hallucinations, although less common, may also occur, causing individuals to see things that are not there. These hallucinations can be very disturbing and cause significant distress.
Delusions are firmly held beliefs that are not based on reality. Amphetamine-induced psychosis often involves delusions of persecution, where individuals believe they are being threatened, maligned, or persecuted in some way. For example, a person may experience paranoid delusions of being followed or watched, accompanied by hallucinations that reinforce these beliefs. Delusions of reference are also common, where individuals believe that ordinary events or coincidences have special personal significance. These delusions can lead to feelings of grandiosity, such as believing one is the target of a conspiracy or has a special mission.
The symptoms of amphetamine-induced psychosis often parallel those of organic psychotic disorders like schizophrenia. However, there are some differences. For instance, visual hallucinations are more common in amphetamine-induced psychosis, while thought disorders are less prominent. The presence of several factors, such as long-term amphetamine use, co-occurring substance use disorders, genetic predisposition, and psychiatric comorbidities, can decrease the likelihood of a full recovery from amphetamine-induced psychosis.
Regarding the longest someone has gone without sleep using drugs, there have been several attempts and records claimed over the years. In 1959, radio DJs Dave Hunter and Peter Tripp both attempted to break the sleeplessness record. Tripp took Ritalin, an energy-giving drug, and managed to stay awake for over 140 hours. In 1963-1964, Randy Gardner, a 17-year-old high school student, broke the record by staying awake for 264 hours (11 days). Gardner's record was broken multiple times, with the last recorded record before Guinness World Records ceased accepting attempts for safety reasons being held by Robert McDonald, who stayed awake for 453 hours and 40 minutes (18 days and 21 hours).
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Captagon, a stimulant, can cause insomnia and sleep deprivation
Sleep deprivation is a direct result of the stimulant effect of Captagon. In a study, 92.9% of the subjects experienced insomnia while using Captagon, and 50% reported that insomnia was always present during its use. The periods of inability to sleep increased with the increase in the daily dosage of Captagon.
Captagon, also known as fenethylline, was first synthesized in Germany in 1961 as a central nervous system stimulant. It was initially marketed in Europe and the Middle East in the 1960s as an over-the-counter product that substituted for amphetamines. However, it was soon made prescription-only. The commercial marketing of Captagon mainly occurred in Europe and the Middle East in the 1960s, when the drug was indicated for attention deficit disorder, narcolepsy, and as a central nervous system stimulant. These early products were offered as tablets containing 50 mg of fenethylline, which metabolized in the body into amphetamine and theophylline. Theophylline is a weaker stimulant, similar to caffeine, and has been associated with arrhythmias and gastrointestinal side effects at supratherapeutic doses. Amphetamine, on the other hand, can be considered the main metabolite and acts as a central nervous system stimulator.
Captagon has been reported to cause psychosis, visual hallucinations, visual distortions, acute heart failure, seizures, and acute myocardial infarction. Other side effects include tachycardia, increased body temperature, rapid respiration, lethargy, and depression. Long-term users of Captagon may also develop malnutrition as the drug can reduce appetite and interest in food. The synergistic relationship between Captagon usage and sleep deprivation may cause acute psychotic states. In the aforementioned study, 86% of patients connected the disappearance of psychosis to their ability to sleep after periods of sleep deprivation.
While Captagon can cause insomnia and sleep deprivation, it is difficult to determine the longest someone has gone without sleep using drugs. This is because the Guinness World Records ceased accepting new attempts for sleep deprivation records in 1997 due to safety concerns. Before this, the record was held by Robert McDonald, who stayed awake for 18 days and 21 hours (453 hours and 40 minutes). However, there have been reports of people breaking this record, such as Tony Wright in 2007. One of the most well-known cases of sleep deprivation is that of Randy Gardner, who stayed awake for 11 days and 24 minutes (264.4 hours) in 1963-1964 when he was 17 years old. Gardner's record attempt was carefully observed, and he reportedly experienced no serious negative effects at the time, although he did develop serious insomnia around 2007, which he attributed to his participation in the sleep study decades earlier.
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Sleep deprivation can cause paranoia, memory issues, and mood changes
Sleep deprivation can have serious impacts on a person's health and well-being. While the effects of short-term sleep loss are reversible, chronic sleep deprivation can have long-lasting consequences. One of the most famous cases of sleep deprivation is the Randy Gardner sleep deprivation experiment. In 1963, Gardner stayed awake for 264 hours (11 days) breaking the previous world record.
During his experiment, Gardner experienced mood changes, problems with concentration and short-term memory, paranoia, and hallucinations. On the eleventh day, when asked to subtract seven repeatedly from 100, he stopped at 65 and couldn't remember what he was doing. Despite this, Gardner appeared to be in excellent health at a press conference on the final day of his experiment. Sleep researchers who monitored his recovery noted changes in his sleep structure, and Gardner himself reported serious insomnia decades later, which he attributed to his participation in the sleep study.
The link between sleep deprivation and paranoia has been the subject of extensive research. Studies have found a strong association between sleep problems and psychotic-like experiences, including paranoia. Sleep difficulties are a common feature of schizophrenia, and insomnia is a risk factor for the development of emotional disorders. Clinical experience also indicates that individuals with persecutory delusions often have trouble falling and staying asleep. Furthermore, the stressful experience of insomnia can lead to a lowering of mood and anomalies of experience that contribute to paranoid thoughts.
In addition to paranoia, sleep deprivation can cause memory issues. Even short-term sleep loss can impair brain functions, including memory formation and consolidation. Sleep is vital for flushing out toxic waste products that accumulate in the brain during wakefulness. Disrupted sleep can also lead to poor concentration, reduced reaction times, and altered mood. In children, it can affect behavior and school performance.
While the exact limit to how long a human can stay awake is unknown, it is clear that sleep deprivation can have significant negative consequences. The Guinness Book of World Records no longer tracks sleep deprivation records due to the health dangers associated with severe sleep loss. Even small amounts of insufficient sleep can have detrimental health effects.
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