
Zopiclone is a prescription sleeping pill used to treat insomnia in adults. It is a non-benzodiazepine hypnotic drug that works by binding to a receptor in the brain called the gamma-aminobutyric acid type A (GABAA) receptor and enhancing the action of gamma-aminobutyric acid (GABA), a chemical messenger that has a calming effect. Zopiclone is typically recommended for short-term use (7-14 days) as it can cause tolerance, dependence, and addiction if used long-term. It may also cause side effects such as sleepwalking, confusion, and impaired driving skills. Due to these potential side effects, it is important for patients taking zopiclone to ensure they will have at least 7-8 hours of uninterrupted sleep and refrain from driving or operating machinery until they know how the medication affects them.
| Characteristics | Values |
|---|---|
| Type of Drug | Non-benzodiazepine hypnotic |
| Uses | Short-term treatment of insomnia |
| Effectiveness | Reduces sleep latency, increases sleep duration, decreases nocturnal awakenings |
| Mechanism of Action | Binds to gamma-aminobutyric acid type A (GABAA) receptor, enhancing gamma-aminobutyric acid (GABA) |
| Dosage | Adults: 7.5mg tablet before bedtime. Elderly: 3.75mg or 7.5mg tablet. People with liver/kidney problems: 3.75mg or 7.5mg tablet |
| Side Effects | Sleepwalking, unusual behaviour, bitter/metallic taste, sleep disturbances, cognitive impairment, daytime sedation, motor incoordination, increased risk of accidents/falls, tolerance, dependence, addiction, withdrawal symptoms, impaired driving skills, drowsiness when combined with opioids |
| Precautions | Avoid alcohol, caffeine, and operating machinery within 12 hours of taking zopiclone |
| Brand Name | Zimovane |
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What You'll Learn
- Zopiclone is a prescription sleeping pill used to treat insomnia
- It is a non-benzodiazepine hypnotic drug with similar benefits and side effects
- Zopiclone reduces sleep latency, increases sleep duration, and decreases nocturnal awakenings
- It is not recommended for long-term use due to the risk of tolerance, dependence, and addiction
- Side effects may include sleepwalking, unusual behaviour, and impaired driving skills

Zopiclone is a prescription sleeping pill used to treat insomnia
Zopiclone was introduced in the 1980s as a treatment for insomnia and is considered a "Z drug," along with zolpidem and zaleplon. It has a different chemical structure from benzodiazepines but binds to the same cell receptors, offering a potentially safer alternative with similar benefits. Zopiclone is often called a short-acting hypnotic due to its quick elimination from the body, with a 'half-life' of about 5 hours.
While zopiclone can be effective in treating insomnia, it is important to be aware of its potential side effects and risks. It can cause sleepwalking and other unusual behaviours, such as driving, eating, or making phone calls while not fully awake. It is recommended to ensure at least 7 to 8 hours of uninterrupted sleep when taking zopiclone to reduce the risk of side effects. Additionally, zopiclone may cause confusion, drowsiness, and impaired driving skills, especially in older individuals. It is advised not to drive or operate machinery until you know how zopiclone affects you.
The use of zopiclone has been associated with a risk of dependence and addiction, particularly when taken for extended periods or at higher than prescribed doses. It is important to follow the prescribed dosage and duration of treatment to minimise this risk. Additionally, zopiclone should be used with caution in individuals with a history of mental health problems, drug or alcohol abuse, or liver disease, as these factors can increase the risk of adverse effects.
Zopiclone can interact with other substances and medications, including alcohol, opioids, and certain mental health medications. It is important to avoid alcohol consumption while taking zopiclone as it can enhance its effects, leading to deep sleep and potential breathing difficulties. Additionally, caffeine should be avoided as it can interfere with the effectiveness of zopiclone. Always consult a healthcare professional before taking zopiclone and provide a full disclosure of any other medications or substances being used.
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It is a non-benzodiazepine hypnotic drug with similar benefits and side effects
Zopiclone is a medication used to treat insomnia in adults. It belongs to a group of drugs called non-benzodiazepine hypnotics. While it has a different structure to benzodiazepine hypnotics, it has a similar mechanism of action and offers similar benefits and side effects.
Zopiclone works by binding to a receptor in the brain called the gamma-aminobutyric acid type A (GABAA) receptor and enhancing the action of gamma-aminobutyric acid (GABA), a chemical messenger that has a calming effect. This helps to reduce the amount of time it takes to fall asleep, increase the amount of total sleep time, and decrease the number of nocturnal awakenings.
As a non-benzodiazepine hypnotic, zopiclone was introduced as a safer alternative to benzodiazepines, which can be highly addictive and lead to dependence. However, zopiclone itself also carries a risk of dependence and addiction, particularly with long-term use or when taken at higher than prescribed doses. It is generally recommended for short-term treatment, typically 7 to 14 days, to reduce these risks.
The benefits and side effects of zopiclone are similar to those of benzodiazepines. One of the main advantages is its ability to improve sleep by reducing sleep latency, increasing sleep duration, and decreasing nocturnal awakenings. However, it also causes impairments in body balance and standing steadiness, similar to benzodiazepines. These impairments can increase the risk of falls and accidents, especially in older adults. Zopiclone may also cause sleepwalking or other unusual behaviours, such as driving, eating, or making phone calls, while not being fully awake. Additionally, it can cause a bitter or metallic taste, reported in about 10% of people.
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Zopiclone reduces sleep latency, increases sleep duration, and decreases nocturnal awakenings
Zopiclone is a medication used to treat insomnia, a sleeping problem characterised by difficulty falling or staying asleep. It belongs to a group of drugs called non-benzodiazepine hypnotics, which have a similar structure and effects to benzodiazepine sedative hypnotics but with some distinct advantages. Zopiclone is particularly effective in reducing sleep latency, increasing sleep duration, and decreasing nocturnal awakenings.
Firstly, zopiclone reduces sleep latency, or the amount of time it takes to fall asleep. By binding to the gamma-aminobutyric acid type A (GABAA) receptor in the brain, zopiclone enhances the action of gamma-aminobutyric acid (GABA), a chemical messenger that induces a calming effect. This mechanism helps individuals fall asleep more quickly.
Secondly, zopiclone increases sleep duration, ensuring that individuals remain asleep for a longer period. It does so by prolonging the N2 and N3 stages of sleep while decreasing the total amount of time spent in the REM stage. This alteration in sleep architecture helps maintain uninterrupted sleep.
Thirdly, zopiclone decreases nocturnal awakenings, reducing the number of times individuals wake up during the night. This effect is also related to its impact on the REM stage of sleep, as reducing REM sleep can decrease the likelihood of awakenings.
While zopiclone can be effective in the short term, it is important to note that it is generally not recommended for long-term use. Prolonged use of zopiclone may lead to tolerance, dependence, and addiction. Additionally, it can cause side effects such as sleepwalking, confusion, and impaired driving skills. Therefore, it is crucial to follow the prescribed dosage and duration for zopiclone and consult a healthcare professional if any unusual symptoms occur.
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It is not recommended for long-term use due to the risk of tolerance, dependence, and addiction
Zopiclone is a prescription sleeping pill used to treat insomnia. It is a non-benzodiazepine hypnotic that works by binding to a receptor in the brain called the gamma-aminobutyric acid type A (GABAA) receptor and enhancing the action of gamma-aminobutyric acid (GABA), a chemical messenger that has a calming effect. While zopiclone can be effective in treating insomnia, it is not recommended for long-term use due to the risk of tolerance, dependence, and addiction.
Tolerance to zopiclone can develop with regular, long-term use, meaning that higher doses of the drug would be required over time to achieve the same effects. This can lead to dependence, which is characterised by physical and psychological symptoms of withdrawal and rebound insomnia if the medication is stopped suddenly. The risk of dependence is greater when zopiclone is used for more than four weeks, in higher doses, and in patients with a history of mental health disorders, substance abuse, or alcohol use.
Additionally, long-term use of zopiclone may lead to addiction. While zopiclone was initially believed to be less addictive than benzodiazepines, recent studies have shown that addiction and habituation are possible. Patients with a history of drug or alcohol abuse are at a higher risk of developing an addiction to zopiclone.
The potential for tolerance, dependence, and addiction makes zopiclone unsuitable for long-term use. It is typically recommended for short-term treatment, ranging from 7 to 14 days, and should be used with caution, especially in patients with relevant medical histories. It is important to follow the prescribed dosage and duration of treatment to minimise the risks associated with zopiclone.
Furthermore, zopiclone has been associated with impaired driving skills and psychomotor function, similar to benzodiazepines. Long-term users of hypnotic drugs for sleep disorders may only develop partial tolerance to these adverse effects, and studies have shown an increased rate of motor vehicle accidents even after one year of use. Therefore, caution must be exercised when operating machinery or driving after taking zopiclone, and it is generally recommended to refrain from these activities for at least 12 hours post-consumption.
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Side effects may include sleepwalking, unusual behaviour, and impaired driving skills
Zopiclone is a medication used to treat insomnia in adults. It is a non-benzodiazepine hypnotic sleeping pill that helps reduce the amount of time it takes to fall asleep, increases sleep duration, and decreases nocturnal awakenings. Zopiclone starts to work within an hour of ingestion. It works by binding to the gamma-aminobutyric acid type A (GABAA) receptor in the brain and enhancing the action of gamma-aminobutyric acid (GABA), a chemical messenger that has a calming effect.
While zopiclone can be effective in treating insomnia, it may also cause several side effects, including sleepwalking and unusual behaviour. Those taking zopiclone may experience sleepwalking episodes and engage in activities such as driving, eating, making phone calls, or having sex while not being fully awake. These behaviours can occur even without the influence of alcohol or other medications, and individuals may not remember these activities the next morning.
The potential side effects of zopiclone also include impaired driving skills. It is advised that individuals should not operate dangerous machinery or drive motor vehicles for at least 12 hours after taking zopiclone. This is because zopiclone can impair an individual's alertness and coordination, increasing the risk of accidents. Even the next morning, individuals should exercise caution as the effects of the medication may still be present.
The unusual behaviour associated with zopiclone can be dangerous and unpredictable. It is important for individuals taking zopiclone to ensure they can get at least 7 to 8 hours of uninterrupted sleep to reduce the risk of these side effects. If any such side effects occur, individuals should stop taking the medication and consult their doctor or healthcare provider immediately.
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Frequently asked questions
Zopiclone is a prescription sleeping pill used to treat insomnia in adults. It is recommended for short-term use only (7-14 days) and should not be taken for more than 4 weeks as it may cause tolerance, dependence, and addiction.
Zopiclone is a non-benzodiazepine hypnotic drug. It has a similar mechanism of action to benzodiazepines, affecting the GABAA receptor in the brain, but it has a different chemical structure.
Common side effects of Zopiclone include sleepwalking, sleep-eating, making phone calls, or other unusual behaviours while not being fully awake. It can also cause a bitter or metallic taste, increased daytime fatigue, impaired driving skills, and withdrawal symptoms when stopped.

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