
Sleep disorders and disturbances are a common problem, with an estimated 13-33% of Australians experiencing some form of insomnia. People often turn to short-term medication or herbal supplements to alleviate symptoms. Lactium is a milk protein that has been shown to improve sleep quality and length and reduce anxiety and stress. It is often combined with the amino acid L-theanine and magnesium. Several studies have been conducted to test the effectiveness of Lactium in improving sleep, with varying results. While some studies have shown improvements in sleep quality and duration, others have found no significant differences between the placebo and Lactium groups.
| Characteristics | Values |
|---|---|
| Definition | Lactium is a milk protein |
| Generic Name | Bioactive milk-derived peptides |
| Composition | Amino acid chains concentrated from casein, derived from cow milk |
| Function | Acts on GABA receptors |
| Benefits | Improves sleep, reduces stress and cortisol levels, induces relaxation, improves mental function |
| Dosage | 300 mg at bedtime |
| Forms | Tablet, lotion |
| Commercial Name | LTC-022 |
| Placebo-Controlled Trials | Showed improvement in sleep quality and reduced sleep disturbances |
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What You'll Learn

Lactium is a milk protein that improves sleep quality and length
Sleep disturbances and insomnia are common issues that can be triggered by factors such as ill health, medication, stress, and other external circumstances. While these disturbances often resolve without treatment once the trigger is eliminated, many people turn to short-term medication or herbal supplements for relief.
Lactium is a milk protein that has been shown to improve sleep quality and length. Developed in France, it is the generic name of bioactive milk-derived peptides. They are amino acid chains concentrated from casein, derived from cow's milk, that act on GABA receptors.
Several studies have been conducted to evaluate the effectiveness of Lactium in improving sleep quality. One double-blind, randomized, placebo-controlled trial assessed the impact of LTC-022, a commercially available dietary supplement containing Lactium and L-theanine, on enhancing sleep quality. The study found that participants who received LTC-022 for 8 weeks experienced improvements in sleep quality, with increased total sleep time and sleep efficiency, as well as decreased sleep latency and wake after sleep onset. Another study, which evaluated the effects of alpha-s1 casein hydrolysate (a form of Lactium) on sleep quality, found that participants who took 300 mg of Lactium daily for 4 weeks experienced significant improvements in subjective sleep quantity and quality.
In addition to improving sleep, Lactium has also been found to reduce stress and anxiety. It is often combined with the amino acid theanine and the mineral magnesium in over-the-counter formulations. One brand, De-Stress, contains pure Lactium and is typically dosed between 150-450 mg at bedtime.
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It reduces anxiety and stress
Lactium is a milk protein that has been shown to improve sleep quality and length, as well as reduce occasional stress and anxiety. It is often combined with the amino acid theanine and the mineral magnesium in over-the-counter formulations. One such formulation, De-Stress, is typically dosed between 150-450 mg at bedtime.
Lactium is the generic name for bioactive milk-derived peptides. They are amino acid chains concentrated from casein, derived from cow's milk, that act on GABA receptors. GABA is a neurotransmitter in the brain that sends chemical messages that help regulate communication between the brain and the nervous system. It plays a key role in inducing relaxation, improving mental function, and reducing stress and anxiety.
Several studies have been conducted to evaluate the impact of Lactium on stress and sleep disorders. One such study, involving 122 participants in France, 111 in the USA, and 105 in China, showed that Lactium significantly improved stress and sleep. After one month of supplementation, overall satisfaction was 75% in France, 70% in China, and almost 90% in the USA.
Another study, a double-blind, randomized, placebo-controlled trial, evaluated the effects of Lactium and L-theanine on sleep disturbance in 40 adults. The participants took either a supplement or a placebo orally for 8 weeks, and the results showed that Lactium and L-theanine alleviated sleep disturbances.
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It is an alternative to medication for insomnia
Sleep disturbances and insomnia are common issues that can be triggered by factors such as stress, ill health, or changes in medication or circumstances. While insomnia often resolves without treatment once the trigger is eliminated, many people turn to short-term medication or herbal supplements for relief.
Lactium is a milk protein that has been shown to improve sleep quality and length while reducing anxiety and stress. Developed in France, it is the generic name for bioactive milk-derived peptides, which are amino acid chains concentrated from casein, derived from cow's milk, that act on GABA receptors.
Lactium has been found to be an effective alternative to medication for insomnia. In a double-blind, randomized, placebo-controlled clinical study, a commercially available dietary supplement containing Lactium and L-theanine, was found to alleviate sleep disturbances in adults. The study, which included 40 participants, lasted for 8 weeks, with participants receiving either the supplement or a placebo. The primary endpoint was sleep quality, which was measured using the PSQI, a widely applied assessment tool in clinical and non-clinical practice. The results showed that Lactium supplementation significantly improved sleep quality, with increased total sleep time and sleep efficiency, and reduced sleep latency and wake after sleep onset.
Another study, a double-blind, randomized, placebo-controlled crossover trial, examined the effects of Lactium on a community-based sample of 48 Korean adults with mild to moderate sleep disturbances. The regimen of 300 mg/day of Lactium for four weeks was able to significantly improve subjective sleep quantity and quality. Objective sleep parameters also showed significantly increased sleep efficiency, which was more evident after continuous use for four weeks compared to two weeks. These findings suggest that Lactium can be safely used to address sleep disturbances, particularly for mild to moderate insomnia symptoms.
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It is often combined with magnesium
Lactium is a milk protein that has been shown to improve sleep quality and length, as well as reduce occasional stress and anxiety. It is often combined with magnesium, an anxiolytic, anti-stress mineral that supports healthy cognitive function and mood. Magnesium is also a natural sedative, helping muscles relax and playing a role in insulin sensitivity, calcium absorption, cardiovascular health, protein synthesis, bone health, and energy metabolism.
Magnesium is a gentle approach to reducing anxiety, insomnia, and muscle tension, and it can be taken in three forms: oral magnesium, magnesium salt baths, and magnesium lotion. Oral magnesium is generally dosed to bowel tolerance, with 300 mg being a sufficient dose at bedtime for most people. Magnesium salt baths, in the form of Epsom salt (magnesium sulfate), are a simple approach to relaxation for children and adults. A cup of Epsom salts is added to warm bathwater, and the individual soaks for 20 minutes about an hour before bed. Finally, magnesium lotion can be applied to tense muscles before bed.
The combination of lactium and magnesium is an effective alternative to medication for anxiety and insomnia. One brand, De-Stress, is pure lactium and is usually dosed between 150-450 mg at bedtime. In a study of 40 participants with sleep discomfort, a commercially available supplement containing Lactium and L-theanine was found to alleviate sleep disturbances. Another study of 171 volunteers with mild insomnia found that a combination of lactium, Zizyphus, Humulus lupulus, magnesium, and vitamin B6 improved sleep quality, although there was no significant difference between the treatment and placebo groups.
While there is some evidence that lactium and magnesium can improve sleep, more rigorous clinical studies are needed to confirm their effectiveness.
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It is safe to use for sleep disturbances
Lactium is generally considered safe for improving sleep quality and alleviating sleep disturbances. It is a milk protein that has been shown to help improve sleep quality and length, and reduce occasional stress and anxiety. It is often combined with the amino acid theanine and the mineral magnesium in over-the-counter formulations. One brand, De-Stress, is pure lactium and is usually dosed between 150-450 mg at bedtime. Another study used a dose of 300 mg of Lactium per day for four weeks and found that it significantly improved subjective sleep quantity and quality, with increased total sleep time and sleep efficiency, and reduced sleep latency and wake after sleep onset.
Lactium is a generic name for bioactive milk-derived peptides. They are amino acid chains concentrated from casein, derived from cow milk, that act on GABA receptors. It improves sleep, reduces stress and cortisol levels, induces relaxation, and improves mental function. It is an effective alternative to medication for anxiety and insomnia.
A double-blind, randomized, placebo-controlled clinical study was conducted to evaluate the impact of a commercially available dietary supplement containing Lactium and L-theanine on enhancing sleep quality. The study found that Lactium supplementation alleviated sleep disturbances in adults, with improvements in total sleep time, sleep efficiency, and reduced sleep latency and wake after sleep onset. The study concluded that Lactium could be safely used to help individuals with sleep disturbances, especially those with mild to moderate insomnia symptoms.
It is important to note that while Lactium is generally considered safe, there have been reports of adverse events in some individuals. In one study, two out of four treatment-related adverse events in the group receiving the Lactium complex resulted in permanent discontinuation. However, the majority of secondary outcomes, including daytime functioning, physical fatigue, mood, anxiety, cognitive performance, and stress reactivity, showed similar improvements in both the Lactium and placebo groups. Overall, Lactium is considered a safe and effective option for improving sleep quality and alleviating sleep disturbances.
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Frequently asked questions
Lactium is a milk protein that is derived from cow's milk. It is also known as alpha-s1 casein hydrolysate (ACH).
Lactium works by acting on GABA receptors in the brain. It improves sleep, reduces stress and cortisol levels, induces relaxation, and improves mental function.
Yes, Lactium is a natural sleep aid. It is often combined with the amino acid L-theanine and the mineral magnesium in over-the-counter (OTC) formulations.
The recommended dose of Lactium is between 150-450 mg at bedtime. However, the safe intake amount has been calculated to be 300 mg/day based on safety analyses in animal studies.
There is some evidence to suggest that Lactium can improve sleep quality and duration. In one study, participants who took 300 mg/day of Lactium for four weeks experienced improved sleep quantity and quality, as well as reduced sleep latency and wakefulness after sleep onset. However, another study found no significant differences in sleep quality between the Lactium and placebo groups.



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