Evie Summers
Rexulti is a prescription drug used to treat depression and schizophrenia in adults. It is also approved to treat agitation related to dementia in adults with Alzheimer's disease, as well as schizophrenia in children ages 13 and older. While Rexulti can be effective in treating these conditions, it may cause side effects such as weight gain, sleepiness, dizziness, and restlessness. Notably, sleepiness or drowsiness is a common side effect, which may be beneficial for those seeking help with sleep. However, it's important to consult a doctor before taking Rexulti, as they can advise on potential interactions with other medications and provide guidance on managing side effects.
| Characteristics | Values |
|---|---|
| Uses | Treatment of depression in adults, treatment of agitation related to dementia in adults with Alzheimer's disease, and treatment of schizophrenia in adults and children ages 13 years and older |
| Active ingredient | Brexpiprazole |
| Drug class | Antipsychotic |
| Side effects | Weight gain, sleepiness, dizziness, common cold symptoms, restlessness or feeling like you need to move (akathisia), insomnia, headache, extrapyramidal symptoms (movement-related disorders), blocked nose, tremor, anxiety, tiredness, constipation, seizure, metabolic side effects (high blood sugar, type 2 diabetes, high cholesterol and triglycerides), low white blood cell count, decreased blood pressure (orthostatic hypotension), difficulty swallowing, drowsiness, difficulty thinking and doing normal activities |
| Withdrawal symptoms | Agitation, anxiety, diarrhea, difficulty sleeping, dizziness, nausea, runny nose, vomiting, uncontrollable movements (muscle spasms, tremors, tardive dyskinesia) |
| Precautions | Avoid becoming too hot or dehydrated, do not exercise too much, avoid caffeine later in the day, do not drive or operate machinery until you know how Rexulti affects you |
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What You'll Learn
Rexulti can cause insomnia and tiredness
Rexulti (brexpiprazole) is a prescription drug used to treat depression and schizophrenia in adults. It is also used to treat agitation related to dementia in adults with Alzheimer's disease, as well as schizophrenia in children aged 13 and older. Rexulti is an atypical antipsychotic drug, which means it works by increasing dopamine and serotonin levels in the brain. While Rexulti can be effective in treating these conditions, it is important to be aware of its potential side effects.
One of the notable side effects of Rexulti is its impact on sleep. Some people taking Rexulti may experience insomnia, which refers to difficulty falling asleep or staying asleep. This can be concerning, especially considering that Rexulti is often prescribed for conditions that may already disrupt sleep patterns, such as depression. It is recommended that individuals taking Rexulti who experience insomnia consult their doctor or pharmacist. Healthcare professionals may suggest ways to improve energy levels during the day and recommend treatments to aid sleep at night, such as taking melatonin supplements.
In addition to insomnia, Rexulti can also cause tiredness or sleepiness. This side effect can occur regardless of the quality or quantity of sleep an individual gets. Due to this tiredness, it is advised that individuals taking Rexulti refrain from driving or operating machinery until they know how the medication affects them. If tiredness becomes a concern, it is important to discuss it with a doctor or pharmacist, who can provide guidance and potentially recommend alternative treatments.
While Rexulti can cause insomnia and tiredness, it is important to note that these side effects may not occur in all individuals taking the medication. The impact on sleep can vary from person to person, and some people may not experience any sleep-related issues at all. Additionally, there are strategies that can help mitigate these side effects, such as improving sleep hygiene and avoiding caffeine later in the day.
It is always advisable to consult a healthcare professional before starting or stopping any medication, including Rexulti. They can provide personalized advice, monitor for side effects, and make adjustments as needed to ensure the best possible outcome for each individual.
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Rexulti may cause drowsiness and dizziness
Rexulti (brexpiprazole) is a prescription drug used to treat depression, schizophrenia, and agitation related to dementia in adults. It is also approved for use in children aged 13 and older with schizophrenia. It is an atypical antipsychotic, a newer type of antipsychotic drug that works by increasing dopamine and serotonin levels in the brain.
While Rexulti can be an effective treatment for these conditions, it may cause side effects, including drowsiness and dizziness. Dizziness may occur when rising too quickly from a sitting or lying position, and it can increase the risk of falls. Patients are advised to avoid sudden head movements if they feel dizzy.
Drowsiness or sleepiness is another potential side effect of Rexulti. Patients are warned not to drive or operate machinery until they know how Rexulti affects them. Taking the medication in the evening before bedtime may help mitigate this side effect.
In addition to drowsiness and dizziness, other side effects of Rexulti include weight gain, headache, restlessness or akathisia, insomnia, and increased risk of seizures. It is important for patients to discuss any side effects they experience with their doctor or pharmacist and not to stop taking Rexulti without medical advice.
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Rexulti can increase the risk of death in elderly patients with dementia
Rexulti (brexpiprazole) is a prescription drug used to treat depression, schizophrenia, and agitation related to dementia in adults with Alzheimer's disease. While it can be beneficial for these conditions, it is important to be aware of its potential side effects, one of which is sleepiness or drowsiness. However, it is crucial to note that Rexulti also has a boxed warning regarding the risk of death in certain adults aged 65 years and older.
Rexulti belongs to the group of antipsychotic drugs, specifically the newer second-generation atypical antipsychotics. While it can be effective in treating mental health disorders, its use is associated with a serious boxed warning from the FDA. This warning highlights that Rexulti can increase the risk of death in older adults with psychosis related to dementia. The warning is particularly relevant for elderly patients who have lost touch with reality (psychosis) due to confusion, memory loss, and dementia. As a result, Rexulti is not approved for the treatment of psychosis without agitation associated with dementia due to Alzheimer's disease.
The side effects of Rexulti can vary from mild to severe. Some of the mild side effects include akathisia, which is a constant, uncontrollable urge to move around, often resulting in restlessness or fidgeting. Additionally, Rexulti may cause weight gain, dizziness, common cold symptoms, and sleepiness. However, more serious side effects have been reported, such as an increased risk of seizures, metabolic side effects like high blood sugar and type 2 diabetes, and difficulty regulating body temperature.
While Rexulti may induce sleepiness, it is important to consider the potential risks associated with its use, especially in elderly patients with dementia. The boxed warning regarding the increased risk of death in this population cannot be overlooked. Therefore, before considering Rexulti for sleep, it is crucial to consult a healthcare professional who can assess the benefits and risks for each individual case. Additionally, there are alternative treatments and lifestyle changes that can help improve sleep without resorting to medications like Rexulti.
In summary, while Rexulti may cause sleepiness as a side effect, its use is not primarily focused on sleep aid, and it carries a serious boxed warning regarding the risk of death in elderly patients with dementia. It is always advisable to consult a healthcare professional before taking any medication, especially when considering potential side effects and interactions with other drugs or supplements.
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Rexulti may cause withdrawal symptoms when stopping
Rexulti (brexpiprazole) is a prescription drug used to treat depression and schizophrenia in adults. It is sometimes used in combination with other medications to treat major depressive disorder (MDD) in adults. Rexulti may also be used to treat agitation associated with dementia due to Alzheimer's disease.
Although Rexulti is not considered habit-forming, some people have reported experiencing withdrawal symptoms within a few days of stopping the medication or reducing their dosage. These symptoms may persist for several weeks. Rexulti should be tapered off slowly over several weeks to reduce the risk of withdrawal.
Withdrawal symptoms may include:
- Agitation
- Anxiety
- Diarrhea
- Difficulty sleeping
- Dizziness
- Nausea
- Runny nose
- Vomiting
- Uncontrollable movements, such as muscle spasms, tremors, or tardive dyskinesia
In rare cases, Rexulti may cause Neuroleptic Malignant Syndrome, which includes symptoms such as high body temperature, muscle rigidity, and mental disturbances. If you experience these symptoms, discontinue Rexulti immediately and seek urgent medical advice.
Additionally, Rexulti has been associated with withdrawal symptoms in newborn children exposed to the drug during the third trimester of pregnancy. If you are pregnant or planning to become pregnant, consult your doctor before taking Rexulti.
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Rexulti may cause metabolic side effects
Rexulti (brexpiprazole) is a prescription drug that is used to treat depression and schizophrenia in adults. It is also used to treat agitation related to dementia in adults with Alzheimer's disease, as well as schizophrenia in children aged 13 years and older. Rexulti is an antipsychotic drug, specifically a second-generation atypical antipsychotic, which works by increasing dopamine and serotonin levels in the brain.
While Rexulti can be an effective treatment for these conditions, it is important to be aware of its potential side effects. One notable side effect is its impact on sleep. Rexulti may cause insomnia or difficulty sleeping, as well as sleepiness or drowsiness. This can lead to tiredness during the day, and patients are advised to avoid driving or operating machinery until they know how Rexulti affects them.
Rexulti has also been associated with metabolic side effects. These may include weight gain, high blood sugar, type 2 diabetes, and increased lipid levels such as cholesterol and triglycerides. Patients taking Rexulti should be cautious about their weight and overall metabolic health. Regular monitoring of weight, blood pressure, cholesterol levels, and hemoglobin A1c (a measure of blood sugar over time) is recommended. Adopting a healthy lifestyle, including exercise, a healthy diet, and portion control, can help mitigate the risk of metabolic side effects.
In addition to the metabolic side effects, Rexulti may also cause mild to severe side effects such as headaches, restlessness or akathisia, low blood pressure, nausea, vomiting, and uncontrollable movements. In rare cases, it may lead to Neuroleptic Malignant Syndrome, characterised by high body temperature, muscle rigidity, and mental disturbances. It is important for patients to be aware of these potential side effects and consult their doctor or pharmacist if any symptoms occur or persist.
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Frequently asked questions
Rexulti is a prescription drug used to treat depression and schizophrenia in adults. While it can make you feel sleepy, it is not a sleep aid. Rexulti may also cause insomnia, which refers to problems falling asleep or staying asleep. Consult your doctor or pharmacist if you are experiencing insomnia while taking Rexulti.
Rexulti can cause mild to serious side effects, ranging from weight gain, headache, dizziness, sleepiness, and restlessness. It may also increase your risk of having a seizure or disrupt your body's ability to regulate temperature.
Do not stop taking Rexulti unless directed by your doctor. Some people experience withdrawal symptoms when stopping or reducing the dosage of Rexulti, which may persist for several weeks. Consult your doctor or pharmacist if you are concerned about side effects or withdrawal symptoms.
If you are having insomnia while taking Rexulti, talk to your doctor or pharmacist. They may suggest ways to improve your sleep hygiene, recommend over-the-counter sleep aids or natural remedies, or advise you to try a different medication.
