
Sleeping pills are a common intervention for insomnia and other sleep disorders. They can help you fall asleep and stay asleep. However, it is important to take them only as prescribed, as taking a higher dose than prescribed can increase your risk of an overdose. Overdosing on sleeping pills can lead to death. An overdose can occur even with small quantities in sensitive individuals, and the likelihood of overdose increases when sleeping pills are mixed with other substances, such as alcohol or opioids.
| Characteristics | Values |
|---|---|
| Purpose | To help people with sleep disorders like insomnia fall asleep and stay asleep |
| Availability | Over-the-counter, as natural supplements, or by prescription |
| Side Effects | Constipation, diarrhea, muscle weakness, digestive problems, worsened snoring and sleep apnea |
| Risks | Dependence, rebound insomnia, overdose, parasomnia, sleep-induced injuries, memory issues, balance problems, accidental death |
| Overdose Symptoms | Slowed breathing, unresponsiveness, severe drowsiness, confusion, lethargy, abdominal pain, clumsiness |
| Overdose Treatment | Administer CPR, call 911, activated charcoal, fluids, medication |
| Prevention | Strictly follow prescribed dosage, avoid mixing with alcohol or drugs, store securely |
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What You'll Learn
- Side effects: constipation, diarrhoea, muscle weakness, digestive issues, worsened snoring and sleep apnea
- Overdose risk: mixing with alcohol, opioids, or other drugs increases the chance
- Death: overdose can be deadly, especially with non-benzodiazepine medications
- Withdrawal: stopping medication can cause rebound insomnia and other withdrawal symptoms
- Addiction: long-term use can lead to addiction and dependence on sleeping pills

Side effects: constipation, diarrhoea, muscle weakness, digestive issues, worsened snoring and sleep apnea
Sleeping pills can cause a range of side effects, and it's important to be aware of these before taking them. While they can be effective for insomnia, they are not a long-term solution and can sometimes worsen insomnia over time. This is known as rebound insomnia, where insomnia returns worse than before once you stop taking the medication.
Some common side effects include constipation, diarrhoea, muscle weakness, and digestive issues. Diarrhoea can be caused by the medication drawing water into the gut or by increased muscle contractions in the intestines. It can also be a result of taking a high dose of laxatives or antacids containing magnesium. Constipation can be a side effect of melatonin, a common sleep aid, and older adults may find this particularly difficult to manage.
Sleeping pills can also worsen snoring and sleep apnea, a potentially life-threatening condition. This is true of both over-the-counter and prescription medications. Additionally, muscle weakness may be related to the pills' ability to relax muscles and relieve anxiety.
It is important to consult a healthcare professional before taking any sleep medication, especially if you are pregnant, breastfeeding, or taking other medications.
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Overdose risk: mixing with alcohol, opioids, or other drugs increases the chance
Mixing sleeping pills with alcohol, opioids, or other drugs increases the risk of overdose and can even be deadly. Both sleeping pills and alcohol are central nervous system depressants, and when combined, they amplify their sedative effects, slowing heart rate and depressing the respiratory system. This can lead to permanent bodily damage and even death.
Sleeping pills, such as barbiturates and benzodiazepines, can be addictive and may lead to overdose, especially when taken in excess or combined with other substances. Benzodiazepines, commonly prescribed for anxiety and sleep, include alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium), and lorazepam (Ativan). Alcohol inhibits the metabolism of some benzodiazepines, leading to higher plasma levels and prolonged elimination rates, increasing the risk of overdose.
The combination of alcohol and opioids or benzodiazepines is particularly dangerous as they may have synergistic effects on brain circuits involved in vital physiological functions. Alcohol plays a role in about one in five overdose deaths related to prescription opioids and benzodiazepines each year. Mixing sleeping pills with alcohol or opioids can also increase the risk of developing a poly-drug use disorder and addiction.
Additionally, mixing sleeping pills with alcohol can increase nervous system side effects, such as drowsiness, dizziness, and difficulty concentrating. It can also result in impaired thinking and judgment, memory problems, and slowed or difficulty breathing. Even drinking one alcoholic beverage in combination with a sleeping pill can be dangerous.
It is important to note that the risk of overdose is higher when sleeping pills are taken in high doses or mixed with other central nervous system depressants. If someone becomes addicted to sleeping pills, treatment is available, and seeking help from a healthcare professional is crucial.
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Death: overdose can be deadly, especially with non-benzodiazepine medications
While modern sleeping pills are safer than their predecessors, and death from their use is less likely, it is still possible to overdose and die from taking too many sleeping pills. This is especially true if you take other substances like opioids or alcohol with your sleeping pills.
Sleeping pills are central nervous system depressants that slow down brain activity to help you rest. Taking a higher dose than prescribed or taking pills more often than prescribed can increase your risk of an overdose. Mixing sleeping pills with other substances like opioids or alcohol can also increase the risk of overdose. For example, while a benzodiazepine overdose is rarely fatal on its own, it can be deadly if mixed with opioids.
The likelihood of fatal overdoses has decreased as barbiturates have become less common. However, sleeping pill overdose deaths are still prevalent, with the National Institute on Drug Abuse (NIDA) reporting that drug overdose deaths have increased consistently since 1999, with more than 64,000 deaths reported in 2016. Furthermore, sedative drugs, including barbiturates and benzodiazepines, are among the main causes of these deaths.
People with a history of substance abuse or mental health disorders are at a higher risk of overdose and death. Those who take sleeping pills for extended periods are also at a higher risk of overdose.
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Withdrawal: stopping medication can cause rebound insomnia and other withdrawal symptoms
Sleeping pills are often prescribed to treat insomnia and other sleep disorders. However, they can lead to addiction and cause physical and psychological dependence. This can lead to withdrawal symptoms when trying to quit or reduce the dosage. It is advised to consult a healthcare provider before starting any sleep medication and to follow the prescribed usage to minimize the risk of dependence.
Withdrawal symptoms from sleeping pills can vary from person to person and depend on factors such as the type of pill, overall health, and the length and frequency of use. Symptoms typically begin within 24 to 72 hours after the last dose and can last for several weeks. During the first few days, individuals may experience anxiety, rebound insomnia, mood swings, headaches, and nausea. These initial symptoms may be followed by increased heart rate, sweating, tremors, and continued sleep problems. In some cases, withdrawal symptoms can be severe and even life-threatening, especially if the individual abruptly stops taking the medication ('cold turkey').
To manage withdrawal symptoms and minimize risks, medical professionals recommend gradually tapering off the medication. This involves slowly reducing the dosage over time until the individual is completely off the medication. This process can be challenging and uncomfortable, so it is important to seek professional help and support during the detox process. Cognitive behavioral therapy can also address the psychological aspects of dependence and improve sleep without medication.
Rebound insomnia is a common withdrawal symptom of sleeping pills. It occurs when an individual stops taking sleep medication, and their insomnia returns, often worse than before. This effect can create a cycle of dependence on sleeping pills, as individuals may feel they need to keep taking the medication to manage their insomnia. It is important to work with a healthcare provider to taper off sleeping pills gradually and explore alternative treatments for insomnia, such as cognitive behavioral therapy and sleep hygiene practices.
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Addiction: long-term use can lead to addiction and dependence on sleeping pills
Sleeping pills can be a helpful short-term solution for those experiencing sleep disorders like insomnia. However, long-term use can lead to addiction and dependence, with withdrawal symptoms that can be intense and even life-threatening.
Sleeping pills are central nervous system depressants that slow down brain activity to help individuals rest. Over time, the body can become reliant on these medications, and stopping their use can result in rebound insomnia, where insomnia returns worse than before. This can create a cycle of dependence, with individuals feeling trapped and unable to break the habit. The risk of addiction is present even with appropriate medical use and can occur after just a few weeks of use.
Withdrawal symptoms from sleeping pills can vary from person to person and may include seizures, psychological discomfort, and intense cravings. Medical detox is the safest way to manage these symptoms and prevent life-threatening consequences. The process typically involves tapering off the medication gradually to reduce the severity of withdrawal symptoms.
Sleeping pill addiction and dependence can be challenging to overcome, but recovery is possible with the right treatment and support. Outpatient care, aftercare, and rehab facilities can provide guidance and resources to help individuals achieve freedom from sleep medication. It is important to seek help as soon as possible if addiction or dependence is suspected.
It is worth noting that taking two sleeping pills at once may increase the risk of overdose, especially if combined with other substances like alcohol. Overdosing on sleeping pills can lead to dangerous outcomes, including death. Therefore, it is crucial to follow the prescribed dosage and not exceed it.
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Frequently asked questions
Taking two sleeping pills can lead to an overdose, especially if the recommended dosage is one pill. Overdoses can be deadly and are more likely if you take sleeping pills with other substances like opioids or alcohol.
Symptoms of a sleeping pill overdose can range from mild to severe. Mild symptoms include excessive sleepiness, memory loss, or strange behaviour. More severe symptoms include slowed breathing, unresponsiveness, abdominal pain, and confusion.
If you think you have overdosed on sleeping pills, call 911 immediately. If the victim appears to be gasping for air or has lost consciousness, administer CPR.
To prevent a sleeping pill overdose, it is important to follow the prescribed dosage and avoid taking extra pills. Do not mix sleeping pills with other substances, especially opioids or alcohol.











































