
Before a surgical procedure, patients are administered drugs to induce sleep and prevent pain during the operation. This process is known as general anesthesia and involves the use of several medicines, including propofol, a rapid-acting sedative-hypnotic drug. Propofol is often the first drug administered to knock out the patient, followed by other anesthetics to maintain unconsciousness. It is generally safe and effective, and its effects can be quickly reversed by stopping the infusion. However, it is important for patients to disclose their medical history, allergies, and current medications to their surgeon or anesthesiologist to ensure the safe use of propofol and other anesthetics.
| Characteristics | Values |
|---|---|
| Drug Name | Propofol |
| Drug Class | Non-barbiturate sedative-hypnotic |
| Brand Name | Diprivan |
| Administration | Intravenously |
| Effects | Puts patients to sleep in seconds |
| Side Effects | Tiredness, grogginess, nausea, dry mouth, sore throat, feeling cold or restless |
| Contraindications | Allergies to eggs, soybeans, or soy products |
| Interactions | Sleeping pills, narcotic pain medicine, prescription cough medicine, muscle relaxers, medicine for anxiety, depression, or seizures |
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What You'll Learn
- Propofol is a sedative-hypnotic drug used to induce sleep during surgery
- General anaesthesia involves a combination of medicines
- Patients are monitored closely while under anaesthesia
- Patients should fast before receiving anaesthesia
- Anaesthesia is administered by an anaesthesiologist or a certified nurse anaesthetist

Propofol is a sedative-hypnotic drug used to induce sleep during surgery
Propofol is a common drug used in anesthesia, often as the first drug administered to "knock out" the patient, with other anesthetics then being given to maintain the sleep state. It is considered extremely safe and effective, and patients can be kept under with propofol for extended periods. It is used for both adults and children over two months old.
The drug is also used in intensive care to sedate patients who are intubated and require a mechanical ventilator. Before administering propofol, doctors must be informed of the patient's medical conditions, allergies, and if they are pregnant or breastfeeding. Propofol contains egg lecithin and soybean oil, so it cannot be used on patients allergic to these substances.
After surgery, patients are monitored for side effects from the drug, which can include nausea, a dry mouth, a sore throat, or feeling cold or restless. These side effects typically wear off within a few hours.
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General anaesthesia involves a combination of medicines
Propofol is a common drug used in general anaesthesia. It is a rapid-acting sedative-hypnotic drug that puts people to sleep in seconds. It is administered intravenously and is used in both adults and children over two months old. Propofol is generally safe, but patients should inform their doctors about their medical conditions, allergies, and whether they are pregnant or breastfeeding.
Other medicines may be used in combination with propofol to maintain general anaesthesia. These could include local anaesthetics, which keep patients sleepy but not fully asleep.
Before surgery, patients may be asked to stop taking certain medications, such as blood-thinning medicines, and to fast for a certain period. A complete medical history, including allergies, health conditions, and medications, will be taken to determine the type and amount of anaesthesia required.
During surgery, patients are monitored very closely, and their blood pressure, pulse, and breathing are checked to ensure they are safe and comfortable.
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Patients are monitored closely while under anaesthesia
General anaesthesia involves the use of certain medicines to put patients to sleep so they do not feel pain during surgery. Patients are closely monitored while under anaesthesia to ensure their safety and well-being. Anaesthesia often involves multiple medications, which may be administered intravenously or inhaled as a special gas through a mask.
An anaesthesiologist, a medical doctor specialising in anaesthesia, pain management, and critical care, is responsible for planning, administering, and monitoring anaesthesia during surgery. They may be assisted by a certified registered nurse anaesthetist. Before the procedure, the anaesthesiologist takes a detailed medical history, including allergies, health conditions, medications, and previous anaesthesia experiences, to determine the type and dosage of anaesthesia required.
During anaesthesia, the patient's vital signs, such as blood pressure, pulse, and breathing, are closely monitored. Modern monitoring modalities, such as derived electroencephalogram (EEG) depth of anaesthesia and cardiac output monitors, provide early warnings of any deterioration in the patient's condition. The anaesthesiologist can adjust the depth of anaesthesia as needed during the surgery.
After the surgery, patients are monitored in the recovery phase until they wake up from the anaesthesia. They may experience side effects such as nausea, vomiting, a dry mouth, sore throat, chills, or confusion, which the medical team will manage. Patients are advised to follow their surgeon's instructions and care for their surgical wound appropriately during recovery.
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Patients should fast before receiving anaesthesia
Patients are often advised to fast before receiving anaesthesia. This is because vomiting and nausea are common side effects of anaesthesia, and having an empty stomach can help prevent these complications. This is especially important in the case of gastrointestinal (GI) surgery, where food in the GI tract could complicate the procedure and lead to infection.
The length of the fasting period depends on the patient's procedure, medical history, and diagnosis. In some cases, patients may be asked not to eat or drink anything after midnight on the night before the surgery. However, clear liquids are usually allowed up to two hours before anaesthesia. These include water, black coffee or tea, pulp-free juices, certain energy drinks, gelatin, and clear broth. Chewing gum is also permitted, as it is now considered safe and can help relieve pre-surgical anxiety.
It is important to note that fasting before anaesthesia is a safety measure to prevent aspiration, which is when patients inhale their stomach contents while sedated. Aspiration is a serious complication that can occur during anaesthesia, and an empty stomach reduces this risk. Patients should always follow the specific recommendations of their surgical team regarding fasting before surgery.
Propofol is a drug commonly used during surgery to induce and maintain sleep. It is typically administered by an anaesthesiologist or a certified registered nurse anaesthetist. Patients should inform their doctor about any medical conditions, allergies, or medications they are taking before receiving propofol to ensure its safe use.
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Anaesthesia is administered by an anaesthesiologist or a certified nurse anaesthetist
Anaesthesia is a medical specialty concerned with the total perioperative care of patients before, during, and after surgery. It involves the administration of anaesthesia, intensive care medicine, critical emergency medicine, and pain medicine. Anaesthesia is administered by an anaesthesiologist or a certified nurse anaesthetist.
An anaesthesiologist is a physician who has specialised in anaesthesiology. In some countries, an anaesthetist is synonymous with an anaesthesiologist, while in others, an anaesthetist is a non-physician. In the UK, for example, an anaesthetist is a doctor who has undertaken postgraduate specialist training in anaesthesia, intensive care medicine, and pain management. They meet with the patient and surgical team to plan the most appropriate anaesthetic for the individual patient and remain with them throughout the operation.
In the US, the term 'anaesthetist' is used only to refer to a physician practising in the field; non-physicians use other titles such as a physician assistant. In Australia and New Zealand, the specialty is referred to as anaesthesia or anaesthetics, and specialists are called anaesthetists. They are represented by the Australian Society of Anaesthetists and the New Zealand Society of Anaesthetists.
Anaesthesia often involves more than one medicine. Some medicines are administered intravenously, while others are gases that are inhaled through a mask. One such drug is propofol, which is used to put patients to sleep and keep them asleep during general anaesthesia. It is used in adults and children aged two months and older. Patients should inform their doctor about any allergies or medical conditions before receiving propofol.
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Frequently asked questions
Propofol is a common drug used to put patients to sleep before surgery. It is a non-barbiturate sedative-hypnotic drug that is administered intravenously.
Propofol is a fast-acting drug that puts people to sleep in seconds. It is often used in combination with other anesthetics to keep the patient under during surgery.
Propofol is considered extremely safe, and patients typically wake up with normal vital signs. However, some patients may experience nausea, a dry mouth, a sore throat, or cold or restless feelings.











































