
If you're experiencing difficulty breathing while sleeping, you may be suffering from sleep apnea, a common disorder that causes the airways to collapse or become blocked. Obstructive sleep apnea (OSA) occurs when the muscles in the throat relax, causing the surrounding tissue to press on the windpipe and block air movement. Central sleep apnea (CSA) happens when the brain fails to send signals to the muscles that regulate breathing. Sleep apnea can cause you to stop breathing for 20 to 30 seconds at a time, numerous times a night, and can lead to severe complications, including excessive daytime sleepiness, arrhythmias, and even heart disease if left untreated. Another possible cause of breathing difficulties while sleeping is orthopnea, which is typically a sign of an underlying condition affecting the heart or lungs. If you're experiencing any breathing problems during sleep, it's important to consult a healthcare professional for a proper diagnosis and treatment plan.
| Characteristics | Values |
|---|---|
| Condition | Sleep apnea, orthopnea, paroxysmal nocturnal dyspnea (PND) |
| Symptoms | Unusual breathing patterns, snoring, snorting, gasping, restless sleep, excessive daytime sleepiness, arrhythmias |
| Causes | Blocked or narrowed airways, large neck or collar size, large tongue, obesity, older age, male gender |
| Diagnosis | Video/audio recordings of sleep, apnea/hypopnea index (AHI), sleep study, physical exam, medical history, chest x-ray, echocardiogram, electrocardiogram (EKG), pulmonary function test |
| Treatment | Lifestyle changes (avoid alcohol/sleep-inducing medicines, sleep on side/front, weight loss), continuous positive airway pressure (CPAP) devices, surgery (windpipe opening, tonsil/adenoid removal, pacemaker implantation) |
| Complications | Interrupted sleep cycle, stress on heart, high blood pressure, heart disease, stroke, diabetes, headache syndromes |
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What You'll Learn
- Sleep apnea: a condition that affects your breathing while you sleep
- Obstructive sleep apnea: when airways collapse or are blocked
- Central sleep apnea: when the brain stops sending signals to muscles that regulate breathing
- Orthopnea: shortness of breath when lying down, caused by underlying conditions
- Paroxysmal nocturnal dyspnea: shortness of breath that wakes you up at night

Sleep apnea: a condition that affects your breathing while you sleep
Sleep apnea is a condition that affects your breathing while you sleep. It is characterised by unusual breathing patterns, such as fast breathing that gets deeper, then shallower again, until breathing stops before starting again. This condition can affect both children and adults, with risk factors including age, male gender, and obesity. Sleep apnea can cause severe or life-threatening complications, including excessive daytime sleepiness, arrhythmias, and even heart failure.
There are two main types of sleep apnea: obstructive sleep apnea (OSA) and central sleep apnea (CSA). OSA occurs when the muscles in the throat relax during sleep, causing the surrounding tissue to block the airway and pause breathing. CSA, on the other hand, is caused by the brain temporarily stopping sending signals to the muscles that regulate breathing. A third, less common type is mixed or complex sleep apnea, which is a combination of both OSA and CSA.
The most telltale symptom of OSA is loud snoring, caused by air squeezing through the narrowed or blocked airway. This snoring may be interrupted by long silent periods, followed by a loud snort and gasp as the person attempts to breathe again. People with OSA may also wake up gasping for air. However, many people with OSA are unaware of their breathing interruptions during sleep, and it is often a sleep partner or family member who notices the loud snoring, gasping, and snorting.
If you suspect you or a loved one has sleep apnea, it is important to seek medical advice. A healthcare provider will take your medical history and perform a physical exam, possibly including tests such as a chest X-ray, echocardiogram, or electrocardiogram (EKG). They may also recommend a sleep study to characterise your breathing patterns while asleep. Treatment options for sleep apnea include lifestyle changes, such as avoiding alcohol and sleeping on your back, as well as continuous positive airway pressure (CPAP) devices that help keep the airway open during sleep.
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Obstructive sleep apnea: when airways collapse or are blocked
Sleep apnea is a condition that affects your breathing while you sleep, preventing restful sleep and potentially impacting your physical and mental health. Obstructive sleep apnea (OSA) is a specific type of sleep apnea where the muscles in your throat relax during sleep, causing the surrounding tissue to press on your windpipe and block airflow. This condition can range from mild to severe, with severity measured using the apnea-hypopnea index (AHI), which calculates the average number of apnea (cessation of breathing) and hypopnea (decreased airflow) episodes per hour of sleep. An AHI of greater than 30 indicates severe OSA, while an AHI between 15 and 30 is considered moderate, and an AHI between 5 and 15 is classified as mild. OSA can affect anyone, but is more common in middle-aged and older adults, and is more prevalent in men than in women. Risk factors for OSA include a large or thick neck (greater than 17 inches for men and 16 inches for women), obesity, and age, as the risk increases as you get older.
The symptoms of OSA include unusual breathing patterns, such as fast breathing that gradually becomes shallower until breathing stops briefly and then resumes. Other symptoms include excessive daytime sleepiness, snoring interrupted by periods of quiet, and arrhythmias. Snoring is one of the biggest indicators of OSA, especially when it is punctuated by moments of silence and then resumes with a loud sound as breathing restarts. These interruptions in breathing can last longer than 10 seconds and occur at least 5 times per hour throughout sleep.
OSA can be diagnosed through a sleep study, which can be conducted in a special facility or at home. Nighttime in-laboratory level 1 polysomnography (PSG) is considered the gold standard for diagnosing OSA. This involves monitoring patients using various sensors and equipment, including electroencephalogram (EEG) leads, pulse oximetry, temperature and pressure sensors, respiratory motion belts, and electromyogram sensors. Unattended portable monitoring and home sleep tests are also suitable for adults with a high pretest probability of sleep apnea and no significant medical comorbidities. These tests include pulse oximetry, heart rate monitoring, and sensors to detect airflow and body position.
Treatment options for OSA aim to keep the airways open and improve breathing during sleep. These include using a continuous positive airway pressure (CPAP) machine and mask, wearing custom-made oral appliances, and surgical procedures such as the removal of adenoids and tonsils or the implantation of nerve stimulators to prevent airway collapse. Lifestyle changes, such as sleeping on the side instead of the back and avoiding alcohol, can also help manage OSA.
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Central sleep apnea: when the brain stops sending signals to muscles that regulate breathing
Sleep apnea is a condition that affects breathing during sleep, preventing restful sleep and causing potential physical and mental health issues. One type of sleep apnea is Central Sleep Apnea (CSA), which occurs when the brain fails to send signals to the muscles that control breathing while asleep.
CSA is characterised by the brain's inability to maintain regular breathing patterns during sleep. Specifically, the issue lies in the brainstem, which is responsible for regulating breathing by detecting changes in carbon dioxide levels in the blood. Typically, when carbon dioxide levels rise, the brainstem prompts the breathing muscles to increase the frequency and depth of breaths, ensuring the body eliminates this waste gas. However, in CSA, the brainstem fails to respond appropriately to elevated carbon dioxide levels, leading to irregular breathing patterns.
The symptoms of CSA are predominantly experienced while awake. Individuals with CSA may experience excessive daytime sleepiness, severe morning headaches, irritability, and difficulty concentrating. They may also wake up abruptly during the night for no apparent reason and exhibit restlessness during sleep.
CSA can be a complication of other underlying conditions, including heart conditions such as congestive heart failure or atrial fibrillation, and neurological conditions such as stroke, amyotrophic lateral sclerosis (ALS), or myasthenia gravis (MG). Certain medications, such as opioid painkillers, and inherited disorders like Rett syndrome or Prader-Willi syndrome, can also contribute to CSA.
Treatment for CSA often focuses on managing the underlying conditions that may be causing or increasing the risk of CSA. Healthcare providers may recommend the use of positive air pressure (PAP) systems, such as continuous positive air pressure (CPAP) machines, bilevel positive air pressure (BiPAP) machines, or adaptive servo-ventilation (ASV) machines. These devices help prevent sleep apnea symptoms by ensuring a continuous supply of pressurised air during sleep.
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Orthopnea: shortness of breath when lying down, caused by underlying conditions
Orthopnea is a condition characterised by shortness of breath when lying down, specifically on one's back. It is different from paroxysmal nocturnal dyspnea (PND), which causes people to wake up at night due to shortness of breath. Orthopnea, on the other hand, can occur when a person is not sleeping, such as when lying down to watch television or at a healthcare provider's office.
People with orthopnea may experience difficulty breathing or feel like they cannot catch their breath. The exact sensation varies from person to person, and the severity of orthopnea can differ for each individual. Some people may require several pillows to prop themselves up so they are not lying flat, while others may find it more comfortable to sleep sitting up on a couch or chair.
Orthopnea is typically a symptom of an underlying medical condition affecting the heart or lungs. One of the main causes is heart failure, but it can also be caused by pulmonary hypertension. If left untreated, orthopnea can lead to or worsen heart disease. Other potential underlying conditions include central sleep apnea (CSA), where the brain fails to send signals to keep breathing-related muscles working during sleep, and obstructive sleep apnea (OSA), where the muscles in the throat relax, causing surrounding tissue to press on the windpipe and block air movement.
If you or someone you know is experiencing orthopnea, it is important to seek medical advice. A healthcare provider will review your symptoms and medical history, and may recommend tests such as a chest X-ray, echocardiogram, electrocardiogram (EKG), or pulmonary function test to diagnose any associated conditions. Treatment options may include addressing the underlying condition, learning how to reposition yourself, supplemental oxygen therapy, medication, surgery, or the use of a medical device such as a pacemaker.
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Paroxysmal nocturnal dyspnea: shortness of breath that wakes you up at night
Paroxysmal nocturnal dyspnea (PND) is a condition characterised by a sudden shortness of breath that occurs a few hours after falling asleep, causing the person to wake up gasping for air or coughing. PND is often associated with heart failure, but it can also be a symptom of other underlying health conditions such as chronic obstructive pulmonary disorder (COPD). It is a classic sign of heart failure, and those who experience it should be evaluated by a doctor to determine the underlying cause.
PND is distinct from general dyspnea, or shortness of breath, which can occur at any time during the day, even during strenuous exercise. While occasional daytime dyspnea is normal, PND is considered abnormal and could indicate a more serious health condition. PND typically occurs one to two hours after falling asleep and can be frightening and distressing for the person experiencing it. They may sit or stand up to try to breathe better, and some people with PND tend to prop themselves up with pillows before sleeping to avoid shortness of breath.
The exact mechanisms behind PND are not fully understood, but they may be similar to those of orthopnea, which is another form of shortness of breath that occurs when lying down, even when a person is awake. Orthopnea is caused by a buildup of fluid in the lungs when a person lies down, and it is often a symptom of heart failure. In the case of PND, theories suggest that it could be related to a decrease in the responsiveness of the respiratory centre in the brain or a decrease in adrenergic activity in the myocardium during sleep.
PND is a symptom that should not be ignored, and those who experience it should seek medical advice. A healthcare provider can help diagnose and address the underlying causes of PND and create a treatment plan to manage symptoms and prevent complications. Video and audio recordings of a person sleeping can be helpful in the diagnostic process, as they can provide evidence of breathing patterns and air movement.
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Frequently asked questions
It could be a sign of sleep apnea, a condition that affects your breathing while you sleep. It could also be a sign of orthopnea, which is difficulty breathing while lying down.
Sleep apnea is a common disorder that causes the airways to collapse or become blocked while you’re asleep, causing your breathing to pause. This can be caused by narrowed or blocked airways due to relaxed throat muscles, or by the brain temporarily stopping sending signals to the muscles that regulate breathing.
Symptoms of sleep apnea include snoring, snorting, gasping, and restless nighttime sleep.
Treatment for sleep apnea aims to keep the airway open while you sleep. Lifestyle changes such as avoiding alcohol or sleeping on your back may help relieve symptoms. Continuous positive airway pressure (CPAP) devices are also commonly used to treat sleep apnea, where a mask is worn over the nose or mouth while sleeping, connected to a machine that pumps air into the airway.











































