
Thorazine, also known as chlorpromazine, is a medication used to treat psychotic disorders such as schizophrenia and bipolar disorder. It is also used to treat severe behavioural problems in children, nausea, vomiting, and anxiety before surgery. While it is not a sleep medication, one of the common side effects of Thorazine is sleepiness or drowsiness, especially when taking typical doses. It is important to note that Thorazine can also cause other side effects, such as movement problems, dry mouth, low blood pressure, weight gain, and blurred vision. Therefore, it is recommended to consult a healthcare provider before taking Thorazine or any other medication to ensure it is safe and appropriate for your individual needs.
| Characteristics | Values |
|---|---|
| Medical Uses | Treats mental health conditions like schizophrenia, bipolar disorder, anxiety, nausea, vomiting, and prolonged hiccups. |
| Used to manage and treat acute psychosis and severe behavioral problems in children. | |
| Can be used to treat insomnia, severe pruritus, and preanesthesia. | |
| Side Effects | Sleepiness, dry mouth, low blood pressure, weight gain, acute movement disorders, sedation, dizziness, blurred vision, hypotension, headache, corneal deposits, lens opacity, cholestatic jaundice, hepatotoxicity, extrapyramidal side effects (EPS) such as acute dystonia, akathisia, parkinsonism, and tardive dyskinesia (TD). |
| May cause sun sensitivity, leading to severe sunburns, blisters, and swelling. | |
| May pass into breast milk and harm a nursing baby. | |
| Abruptly stopping medication may cause withdrawal symptoms such as nausea, vomiting, and loss of appetite. | |
| May cause severe reaction, requiring medical help. | |
| Dosage | Orally as a tablet or liquid with a glass of water. |
| Intramuscular or intravenous injection. | |
| Precautions | Avoid alcohol consumption as it increases sleepiness, affects alertness, and increases the risk of dangerously low blood pressure. |
| Do not drive or operate machinery until you know how the medication affects you. | |
| Avoid sunlight or use sunscreen, a hat, and protective clothing when going out in the sun. | |
| Do not stop taking the medication without consulting a healthcare provider. |
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What You'll Learn

Thorazine (chlorpromazine) is an antipsychotic medication
Chlorpromazine is available in oral tablet or liquid form and is usually taken by mouth with a glass of water. It should be stored at room temperature, protected from light and moisture, and kept out of the reach of children. When taking chlorpromazine, it is important to follow the directions on the prescription label and take doses at regular intervals as advised by a healthcare provider. It is crucial not to stop taking this medication suddenly without medical advice, as it may lead to withdrawal symptoms such as nausea, vomiting, and dizziness.
The medication has various side effects, including movement problems, sleepiness, dry mouth, low blood pressure, and weight gain. It can also cause photosensitivity, making the skin more vulnerable to damage from sunlight, sunlamps, and tanning beds. Additionally, chlorpromazine may lead to hypotension after injection, and it can cause corneal deposits and lens opacity with prolonged use. Combining chlorpromazine with alcohol or certain other medications, such as sedatives, barbiturates, or narcotics, can increase the risk of severe side effects.
Chlorpromazine has been a widely used medication for over fifty years and is considered a "benchmark" drug in the treatment of schizophrenia. It has been particularly effective in controlling manic episodes in bipolar disorder, reducing nausea and vomiting, and managing severe anxiety before surgery. While it is not a perfect medication, chlorpromazine has helped millions of people worldwide and remains a valuable tool in the management of mental health conditions.
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It is used to treat mental health conditions such as schizophrenia and bipolar disorder
Chlorpromazine, marketed under the brand names Thorazine and Largactil, among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia and bipolar disorder. Chlorpromazine belongs to a group of medicines called first-generation (typical) antipsychotics. It blocks some areas in the brain where the natural chemical dopamine works. This lowers the effect of dopamine in the body, which can affect your behaviour and thinking.
Chlorpromazine is also used to treat severe behavioural problems in children, including those with attention deficit hyperactivity disorder. It can be given orally (by mouth), by intramuscular injection (injection into a muscle), or intravenously (injection into a vein). The dose can range from 10 to 25 mg orally every 4 to 6 hours as needed. If used as an intramuscular or intravenous injection, the dose can range from 25 to 50 mg every 4 to 6 hours as needed. It is important to note that chlorpromazine can cause side effects such as movement problems, sleepiness, dry mouth, low blood pressure, and increased weight. It can also make your skin more sensitive to light, which can lead to severe sunburns, blisters, and swelling.
In addition to treating mental health conditions, chlorpromazine is also used to treat nausea and vomiting, anxiety before surgery, and hiccups that do not improve with other measures. It has been used in the treatment of porphyria and tetanus. Chlorpromazine has also been found to be effective in treating symptoms of delirium in hospitalized AIDS patients and as a hallucinogen antidote to block the effects of serotonergic psychedelics. While it is a widely used medication, chlorpromazine may not be suitable for everyone, and it is important to consult a healthcare professional before taking this medication.
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It can be used to treat nausea and vomiting
Chlorpromazine, commonly known by the brand name Thorazine, is a typical antipsychotic medication used to treat psychiatric disorders. It is primarily used to treat psychotic disorders such as schizophrenia and bipolar disorder. However, it has other indications, including the treatment of nausea and vomiting.
Chlorpromazine is a member of the typical antipsychotics or neuroleptic medication category, also known as first-generation antipsychotics. It works by blocking some areas in the brain where dopamine, a natural chemical that affects behaviour and thinking, works. By lowering the effect of dopamine in the body, chlorpromazine can help relieve nausea and vomiting.
The dosage of chlorpromazine for treating nausea and vomiting can range from 10 to 25 mg orally every 4 to 6 hours as needed. If used as an intramuscular or intravenous injection, the dose can be higher, ranging from 25 to 50 mg every 4 to 6 hours. It is important to note that chlorpromazine can cause side effects such as sedation, weight gain, lowering of blood pressure, and movement problems. It can also make individuals more sensitive to light, so it is important to take precautions when exposed to sunlight or other light sources.
While chlorpromazine is commonly used to treat nausea and vomiting, it is not suitable for everyone. For example, it is not recommended for pregnant or breastfeeding individuals as it may pass to the baby through breast milk and potentially cause side effects in newborns. Additionally, it may interact with other medications, such as those that cause dizziness and sleepiness, anticholinergic medicines, barbiturates, opioids, and blood thinners. Therefore, it is important to consult a healthcare provider before taking chlorpromazine to ensure it is safe and appropriate for your specific situation.
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It can cause sleepiness and drowsiness
Chlorpromazine, also known by the brand name Thorazine, is a typical antipsychotic medication primarily used to treat psychiatric disorders such as schizophrenia and bipolar disorder. It is also used to control nausea and vomiting, and to manage severe behavioural problems in children.
Chlorpromazine can cause sleepiness and drowsiness. At high doses, chlorpromazine is sedating and has a calming effect on hospitalised mental health patients. Even at typical doses, chlorpromazine can cause sedation and drowsiness, but this usually passes within a few weeks as the body adjusts to the medication. It is important to note that chlorpromazine can affect alertness and coordination, so activities requiring alertness, such as driving or operating machinery, should be avoided until you know how this medication affects you.
The medication may also interact with other substances, such as alcohol, which can increase sleepiness and sedation, and further impact alertness and concentration. It is therefore important to inform your healthcare provider about any other medications, herbs, or supplements you are taking, as well as your alcohol consumption, to avoid any potential interactions.
In addition to sleepiness and drowsiness, other side effects of chlorpromazine include movement problems, dry mouth, low blood pressure, and weight gain. It is worth noting that older individuals (65+) may be at a higher risk for certain side effects. Therefore, it is crucial to discuss any concerns with your healthcare provider, who can advise on the risks and benefits of chlorpromazine for your specific situation.
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It is not recommended for pregnant or breastfeeding women
Chlorpromazine, also known as Thorazine, is a typical antipsychotic medication primarily used to treat psychiatric disorders such as schizophrenia. It is also used to treat bipolar disorder, acute psychosis, and severe behavioural problems in children. Chlorpromazine is known to cause side effects such as movement problems, sleepiness, dry mouth, low blood pressure, and weight gain.
While chlorpromazine can cause sleepiness or drowsiness, it is not recommended as a sleep aid. This is because it is a potent medication with several side effects and safety considerations.
Pregnant or breastfeeding women should not take chlorpromazine unless prescribed by a doctor. While it is unknown if chlorpromazine can harm an unborn baby, taking the medication during the third trimester of pregnancy could cause symptoms such as agitation, breathing problems, or trouble feeding in the newborn baby. Chlorpromazine can also pass into breast milk and may harm a nursing baby. Therefore, it is crucial for pregnant or breastfeeding women to consult their healthcare provider before taking chlorpromazine.
Additionally, chlorpromazine can affect alertness and coordination, so it is advised not to drive or operate heavy machinery until you know how the medication affects you. The medication can also make your skin more sensitive to light, so caution should be taken to avoid severe sunburns, blisters, and swelling.
It is important to note that chlorpromazine should only be taken under medical supervision, and any changes to the dosage or discontinuation of the medication should be done under the guidance of a healthcare professional.
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Frequently asked questions
Thorazine, or chlorpromazine, is an antipsychotic medication used to treat psychotic disorders such as schizophrenia and bipolar disorder. It is also used to treat nausea and vomiting, anxiety before surgery, and severe behavioural problems in children.
Thorazine is not typically used as a sleep aid. However, it can cause sedation and drowsiness, particularly when first starting the medication. It is important to note that Thorazine is a prescription medication and should only be taken under the advice and supervision of a healthcare professional.
Thorazine has been found to have several side effects, including movement problems, dry mouth, low blood pressure, weight gain, and acute movement disorders. It can also cause hypotension and headaches when administered intravenously. Prolonged use may also cause corneal deposits and lens opacity.









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