
Cetirizine is a second-generation antihistamine medication used to treat mild to moderate allergy symptoms such as sneezing, itching, and watery eyes. It is available over the counter in the US and UK in the form of 5 and 10 mg tablets and capsules. It is also available as a liquid and eye drops. While it is generally safe and effective, it can cause side effects such as drowsiness in over 1 in 10 people, according to the NHS. This is because it blocks the effects of histamine, which is responsible for allergic responses and also plays a role in regulating the sleep-wake cycle in the brain. Mixing cetirizine with alcohol or other drugs that cause sleepiness can increase this effect. Therefore, it is important to be cautious and avoid activities that require alertness or coordination until you know how cetirizine affects you.
| Characteristics | Values |
|---|---|
| Type of Drug | Over-the-counter drug, allergy medication |
| Dosage | 5-10 mg per day, not more than 10 mg in 24 hours |
| Side Effects | Drowsiness, dry mouth, blurred vision, overheating, headache, abdominal pain |
| Precautions | Avoid driving or operating machinery, avoid alcohol, inform your doctor if you are pregnant or breastfeeding |
| Drug Interactions | Sleeping pills, muscle relaxers, tranquilizers, sedatives, anti-seizure medication, anti-depressants, anti-anxiety medication |
| Age Restrictions | Safe for children 6 years and older, older adults may need a lower dose |
| Forms Available | Tablets, capsules, liquid, eye drops, syrup, chewable tablets, dissolvable tablets |
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What You'll Learn
- Cetirizine is an antihistamine that treats mild to moderate allergy symptoms
- It is available over the counter and by prescription
- It is generally safe during pregnancy but may harm a nursing baby
- Side effects include drowsiness, impaired thinking, headaches, and abdominal pain
- It is less likely to cause drowsiness than older antihistamines

Cetirizine is an antihistamine that treats mild to moderate allergy symptoms
Cetirizine is a second-generation antihistamine medication used to treat mild to moderate allergy symptoms. It is available over the counter in the US and UK in the form of 5 and 10 mg tablets, capsules, liquids, and eye drops. It can also be purchased as a 1 mg/mL syrup or in higher doses by prescription. It is an inexpensive, safe, and effective drug that can be taken by adults and children over the age of 6. The typical dosage is one 10-milligram dose per day, although older adults may need to take a lower dose.
When you come into contact with an allergen, your body produces a chemical called histamine, which causes most of the symptoms related to allergic reactions. Cetirizine blocks the effects of histamine, thereby preventing symptoms such as a runny nose, sneezing, itching, and inflammation. It is commonly used to treat seasonal allergies, perennial allergic rhinitis, allergic asthma, and hives.
Cetirizine is less likely to cause side effects such as dangerous drowsiness, dry mouth, blurred vision, and overheating compared to first-generation antihistamines. However, some people may still experience drowsiness as a side effect, and it is recommended that you do not drive or operate machinery until you know how Cetirizine affects you. Other side effects may include headache and abdominal pain. If you are taking other medications that cause sleepiness, it is important to consult your doctor before taking Cetirizine as it may add to the sedating effects.
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It is available over the counter and by prescription
Cetirizine is an antihistamine medication that is used to treat mild to moderate allergy symptoms, such as sneezing, itching, watery eyes, and a runny nose. It is also used to treat allergic rhinitis (hay fever), dermatitis, and urticaria (hives). It is available in the form of capsules, tablets, liquid, and eye drops.
While cetirizine is generally safe and effective, it can cause side effects such as drowsiness, dry mouth, headache, and abdominal pain. According to the NHS, over 1 in 10 people experience mild sedation or fatigue as a side effect. This is because cetirizine blocks the effects of histamine, a natural chemical that is responsible for allergic responses, but also plays a role in regulating the sleep-wake cycle in the brain. As a result, cetirizine can sometimes cause enough sedation to make people feel drowsy.
The likelihood of experiencing drowsiness can depend on the dosage and individual sensitivity to antihistamines. It is important to note that cetirizine can also interact with other substances, such as alcohol, and other medications that cause sleepiness, such as sleeping pills, muscle relaxers, and medications for seizures, depression, or anxiety. Therefore, it is important to inform your doctor or healthcare provider if you are taking any other medications or substances that may interact with cetirizine.
Cetirizine is available over the counter (OTC) in the US in the form of 5 and 10 mg tablets. It is also available as a generic medication and is one of the most commonly prescribed medications in the United States. In 2022, it was the 43rd most prescribed medication, with over 13 million prescriptions. A 20 mg strength of cetirizine is available by prescription only. It is also available as a 1 mg/mL syrup for oral administration by prescription.
Overall, while cetirizine can cause drowsiness in some people, it is generally less sedating than older antihistamine medications. It is important to use caution when taking cetirizine and avoid activities that require alertness or coordination until you know how it affects you.
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It is generally safe during pregnancy but may harm a nursing baby
Cetirizine is an antihistamine medication used to treat symptoms of allergies, such as sneezing, itching, a runny nose, and watery eyes. It is available over the counter under brand names such as Zyrtec and Reactine.
Pregnancy
While there is limited information on the effects of cetirizine during pregnancy, studies suggest that it is generally safe to take. Several studies have found no evidence of an increased risk of miscarriage, birth defects, or other pregnancy-related complications when cetirizine is taken during pregnancy. Animal studies have also failed to reveal any harmful effects on pregnancy, embryofetal development, or postnatal development.
However, it is important to note that most medications cross the placenta and reach the baby, and some medications can affect a baby's growth and development. Therefore, it is always recommended to consult with a healthcare professional before taking any medication during pregnancy, including cetirizine.
Breastfeeding
Cetirizine is considered one of the best choices for breastfeeding mothers who need to take an antihistamine. Studies have shown that only very small amounts of cetirizine get into breast milk, and it has been widely used while breastfeeding without causing any side effects in babies. However, it is still important to monitor the baby for any signs of drowsiness or other symptoms, and to contact a healthcare professional if any concerns arise.
While cetirizine is generally safe during pregnancy and considered a good option for breastfeeding mothers, it is always advisable to consult with a healthcare provider before taking any medication, especially during pregnancy and while breastfeeding.
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Side effects include drowsiness, impaired thinking, headaches, and abdominal pain
Cetirizine is a second-generation antihistamine medication used to treat allergies and allergic reactions. It is available over the counter in the US and UK and is considered a safe and effective drug. However, like any medication, it can cause side effects.
The most common side effects of cetirizine are drowsiness, impaired thinking, headaches, and abdominal pain. Drowsiness occurs in over 1 in 10 people taking cetirizine, according to the NHS. This is because cetirizine blocks the effects of histamine, a natural chemical that is responsible for allergic responses like sneezing and itching. Histamine also plays a role in regulating the sleep-wake cycle in the brain, so by blocking histamine, cetirizine can cause sedation and make you feel drowsy. The likelihood of feeling drowsy can depend on the dosage and individual sensitivity to antihistamines.
Impaired thinking and reactions are also side effects of cetirine, and users are warned not to drive or operate machinery until they know how the medication affects them. It is also advised that users avoid drinking alcohol when taking cetirizine, as this can increase some of the side effects.
Headaches are another common side effect of cetirizine. Abdominal pain is also listed as a side effect, although it is not as commonly reported as the other side effects mentioned.
It is important to note that side effects may vary depending on age, and older adults may need to take a lower dose. It is always recommended to speak to a doctor or healthcare provider before taking any new medication, especially if you are pregnant, planning to become pregnant, or breastfeeding.
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It is less likely to cause drowsiness than older antihistamines
Cetirizine is a second-generation antihistamine, which means it is a newer type of allergy medication. It is taken to help treat allergy symptoms such as a runny nose, itchy or watery eyes, sneezing, or an itchy nose or throat. It may also be used to reduce itching and hives on the skin. It is available over-the-counter and by prescription.
Cetirizine is less likely to cause drowsiness than older antihistamines. However, it can still cause sleepiness in some people. According to the NHS, over 1 in 10 people experience mild sedation or fatigue as a side effect. The likelihood of feeling drowsy can depend on the dosage as well as individual sensitivity to antihistamines. Some people simply process the medication differently.
Antihistamines like cetirizine work by blocking histamine, the natural chemical responsible for allergic responses like sneezing and itching. However, histamine also plays a role in regulating the sleep-wake cycle in the brain. By blocking histamine's actions, cetirizine can sometimes cause enough sedation to make you feel drowsy.
While cetirizine is less likely to cause drowsiness than older antihistamines, it is still important to be cautious when taking it. Don't drive your car or use machinery until you know how your body will respond to cetirizine. If you are pregnant or planning to become pregnant, or if you are breastfeeding, talk to your doctor before taking cetirizine.
Cetirizine can also interact with other substances. For example, avoid consuming alcoholic drinks while taking cetirizine, as this can be dangerous and cause drowsiness or make you less alert. If you take any tranquilizers, sedatives, or sleep aids, make sure to mention this to your doctor before taking cetirizine, as mixing it with drugs that depress your central nervous system can increase sleepiness.
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Frequently asked questions
No, cetirizine is an antihistamine used to treat allergic reactions and is available over the counter.
Yes, cetirizine can cause sleepiness in some people, although it is less sedating than older antihistamine medications. According to the NHS, over 1 in 10 people experience this side effect.
Antihistamines like cetirizine work by blocking histamine, a natural chemical responsible for allergic responses. Histamine also plays a role in regulating the sleep-wake cycle in the brain. By blocking histamine, cetirizine can cause sedation and make you feel drowsy.
Common side effects of cetirizine include drowsiness, dry mouth, headache, and abdominal pain. It can also impair your thinking and reactions, so caution is advised when driving or operating machinery.
If you regularly use medications that cause sleepiness, such as sleeping pills, muscle relaxers, or antidepressants, it is important to consult your doctor before taking cetirizine as it may increase sleepiness.












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