
Trazodone is a medication that was initially prescribed to treat depression. However, it is now also commonly prescribed off-label as a sleep aid, particularly for insomnia. While trazodone is generally safe for adults to take for short-term sleep issues, it is not recommended as a first-line treatment for insomnia, and it is not approved for use in children due to an increased risk of suicidal thoughts and behaviours in this age group. If you are considering taking trazodone, it is important to discuss it with your doctor, as they will need to consider factors such as your age, medical history, and any other medications you are taking.
| Characteristics | Values |
|---|---|
| When to take | At bedtime, after food |
| Dosage | 50-150mg, up to 400mg in some cases |
| Frequency | Once a day |
| Duration | No longer than 1 month without medical advice |
| Side effects | Dizziness, drowsiness, orthostatic hypotension, serotonin syndrome, withdrawal symptoms, suicidal thoughts |
| Interactions | Do not take with MAOIs, alcohol, other sleeping pills, antidepressants, opioid painkillers, St. John's Wort |
| Precautions | Not recommended for children, not to be taken for longer than prescribed, do not stop taking suddenly |
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What You'll Learn
- Trazodone is not recommended for children and young adults due to an increased risk of suicidal thoughts and behaviours
- It is important to discuss side effects and concerns with a doctor before taking trazodone
- Trazodone is typically taken at bedtime, after food, to reduce the chances of feeling sick
- Trazodone may be less expensive than other insomnia drugs and is not considered addictive
- Trazodone is not approved as a first-line treatment for insomnia and should be considered after non-pharmacological methods

Trazodone is not recommended for children and young adults due to an increased risk of suicidal thoughts and behaviours
Trazodone is a medication approved by the FDA for use as an antidepressant. It is also often prescribed as a sleep aid, although this is considered off-label. While trazodone is generally safe for adults, there is limited safety data for children, and it is not recommended for those under 18.
Trazodone has been linked to an increased risk of suicidal thoughts and behaviours in children and young adults. This risk is higher in individuals with a history of such thoughts or behaviours. The FDA has issued a "Black Box Warning" for trazodone, its strongest medication warning, due to this risk. As a result, individuals taking trazodone should be closely monitored for worsening symptoms and the development of suicidal thoughts and behaviours.
Depression and other mental illnesses have been shown to increase the risk of suicidal ideation and behaviour. This risk is further compounded by the use of antidepressants like trazodone, particularly in children and young adults. While trazodone is not approved for use in children, a doctor may prescribe it if they deem the benefits to outweigh the risks.
It is important to note that having depression or another mental illness significantly increases the risk of becoming suicidal. This risk is even higher if there is a family history of bipolar disorder, mania, or suicidal thoughts. Therefore, it is crucial to carefully consider the risks and benefits of taking trazodone or any other antidepressant, especially for children and young adults.
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It is important to discuss side effects and concerns with a doctor before taking trazodone
Trazodone is a medication approved by the FDA as an antidepressant in 1981. Given in lower doses, it may help improve sleep and cause less daytime sleepiness or drowsiness. Although trazodone is commonly used for sleep, it is not recommended as a first-line treatment for insomnia.
Additionally, trazodone may interact with other medications or substances, such as alcohol, other sleeping pills, or antidepressants. These interactions can increase the risk of side effects or cause other health complications. It is important to disclose all medications and supplements being taken to a doctor before starting trazodone.
Furthermore, there are specific populations who should not take trazodone or should do so with caution. For example, trazodone is not recommended for children and young adults due to an increased risk of suicidal thoughts and behaviors. Pregnant individuals should also not take trazodone, as it could harm the baby, although stopping the medication may also pose risks. Breastfeeding individuals should consult a doctor about the potential risks as well.
It is also important to note that trazodone can cause withdrawal symptoms if it is stopped abruptly. Therefore, it is crucial to discuss any plans to discontinue trazodone with a doctor and follow their instructions for slowly reducing the dosage to avoid withdrawal. Overall, discussing side effects, interactions, and concerns with a doctor before taking trazodone is essential to ensure safe and effective use of the medication.
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Trazodone is typically taken at bedtime, after food, to reduce the chances of feeling sick
Trazodone is a medication initially prescribed to treat depression. However, it is also commonly prescribed off-label as a sleep aid. Trazodone is typically taken at bedtime, after food, to reduce the chances of feeling sick.
Trazodone is available in tablet, capsule, and liquid form and is only available via prescription. Doctors usually prescribe trazodone when other antidepressants have not worked or have caused side effects. It can take one to two weeks for trazodone to start working, but it may be four to six weeks before you feel the full benefit.
Trazodone is typically taken at bedtime. If your dose is 300mg or less per day, your doctor will likely advise you to take it as a single dose before bed. As trazodone can make you feel sleepy, taking it at bedtime may help if you have trouble sleeping. It is important to take trazodone only as prescribed by your doctor or healthcare professional.
Trazodone should be taken after a meal to reduce the chances of feeling sick. It is also important to avoid substances like alcohol and other sleeping pills to prevent excessive drowsiness. Other interactions are also possible, so it is important to discuss possible side effects and concerns with your doctor before taking trazodone.
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Trazodone may be less expensive than other insomnia drugs and is not considered addictive
Trazodone is an antidepressant medication that was first approved by the U.S. Food and Drug Administration (FDA) in 1981. It is often prescribed as a sleep aid, although it is not recommended as a first-line treatment for insomnia.
Trazodone may be less expensive than other insomnia drugs because it is available generically. It is also not considered addictive like other medications, such as benzodiazepines. This is because trazodone is not classified as a controlled substance by the FDA, meaning it does not carry the same risks of addiction or abuse.
The risk of addiction associated with trazodone is lower than with classic antidepressants or sleeping tablets such as Ambien (zolpidem), Lunesta (eszopiclone), or Sonata (zaleplon). However, it is important to note that abruptly stopping trazodone can lead to withdrawal symptoms, including insomnia, agitation, anxiety, and increased sleeping issues. Therefore, it is recommended to slowly reduce the dosage over time if you plan to stop taking trazodone.
While trazodone may be less expensive and less addictive than other insomnia drugs, it is important to consider potential side effects and risks. Trazodone has been associated with an increased risk of suicidal thoughts and behaviours, particularly in children and young adults. It can also cause dizziness, fainting, and an irregular heartbeat. Additionally, trazodone may interact with other medications, such as monoamine oxidase inhibitors (MAOIs) and other serotonin-boosting drugs, leading to serious health conditions like serotonin syndrome.
Before taking trazodone or any other sleep aid, it is essential to consult with a healthcare professional to discuss potential benefits and risks. Cognitive Behavioural Therapy for insomnia (CBTi) is recommended as the first line of treatment for insomnia, as it addresses the root cause of the sleep problem rather than just masking the symptoms.
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Trazodone is not approved as a first-line treatment for insomnia and should be considered after non-pharmacological methods
Trazodone is a medication approved for use by the FDA as an antidepressant. However, it has been prescribed off-label as a sleep aid since the 1980s. Off-label use of a medication is a widespread practice, and doctors sometimes prescribe drugs for conditions other than what they were approved for. While trazodone is one of the most commonly prescribed treatments for insomnia, it is not approved as a first-line treatment.
The American Academy of Sleep Medicine does not recommend trazodone as a first-line treatment for insomnia. Instead, it is suggested that non-pharmacological methods should be considered first. These include improving sleep hygiene, practising relaxation methods, and cognitive behavioural therapy (CBT). If these treatments are ineffective, a doctor may then recommend over-the-counter or prescription medications.
Trazodone is generally safe for adults to take for sleep, but there is limited research on its safety for long-term use. It is not recommended for children, as there is little safety data available for this age group. Additionally, trazodone has been issued a ""Black Box Warning" by the FDA due to an increased risk of suicidal thoughts and behaviours in children and young adults.
Before prescribing trazodone, a healthcare professional will consider various factors, such as age, existing health conditions, and any other medications being taken. It may not be safe to take trazodone if you have certain health conditions or are taking other medications that increase serotonin levels, such as antidepressants, opioid painkillers, or herbal supplements like St. John's wort.
If you are considering taking trazodone for sleep, it is important to speak with a healthcare professional. They can advise on potential alternatives, including lifestyle, dietary, and behavioural changes, as well as provide information on the benefits, risks, and appropriate dosage of trazodone.
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Frequently asked questions
Trazodone is a medication approved by the FDA as an antidepressant in adults. Doctors also prescribe it as a sleep aid, although it is not approved for this use.
If you are taking trazodone, it is best to take it in the evening or before you go to bed. Take it after food to reduce the chances of feeling sick.
The dosage of trazodone for treating insomnia typically ranges from 50-150 mg. If you are unsure, consult your doctor, who will prescribe you a dosage based on your age, health conditions, and other medications.


























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